Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Veronika V. Sapozhnikova; Roman V. Kuranov; Inga Cicenaite; Rinat O. Esenaliev; Donald S. Prough

doi:10.1117/1.2909671

Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Veronika V. Sapozhnikova, Roman V. Kuranov, Inga Cicenaite, Rinat O. Esenaliev, Donald S. Prough

Neuroscience & Cell

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

Original language	English (US)
Article number	021112
Journal	Journal of Biomedical Optics
Volume	13
Issue number	2
DOIs	https://doi.org/10.1117/1.2909671
State	Published - 2008

Keywords

glucose
noninvasive monitoring
optical coherence tomography
pressure
tissue

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Biomedical Engineering

Access to Document

10.1117/1.2909671

Cite this

@article{fc5d8595a9684257a9ab913d16477a3f,

title = "Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe",

abstract = "We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.",

keywords = "glucose, noninvasive monitoring, optical coherence tomography, pressure, tissue",

author = "Sapozhnikova, {Veronika V.} and Kuranov, {Roman V.} and Inga Cicenaite and Esenaliev, {Rinat O.} and Prough, {Donald S.}",

note = "Funding Information: This work was supported by the National Institutes of Health (grant #R01 EB001467 from the National Institute for Biomedical Imaging and Bioengineering). The authors thank Dr. Donald J. Deyo for assistance with the animal experiments.",

year = "2008",

doi = "10.1117/1.2909671",

language = "English (US)",

volume = "13",

journal = "Journal of Biomedical Optics",

issn = "1083-3668",

publisher = "SPIE",

number = "2",

}

TY - JOUR

T1 - Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

AU - Sapozhnikova, Veronika V.

AU - Kuranov, Roman V.

AU - Cicenaite, Inga

AU - Esenaliev, Rinat O.

AU - Prough, Donald S.

N1 - Funding Information: This work was supported by the National Institutes of Health (grant #R01 EB001467 from the National Institute for Biomedical Imaging and Bioengineering). The authors thank Dr. Donald J. Deyo for assistance with the animal experiments.

PY - 2008

Y1 - 2008

N2 - We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

AB - We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

KW - glucose

KW - noninvasive monitoring

KW - optical coherence tomography

KW - pressure

KW - tissue

UR - http://www.scopus.com/inward/record.url?scp=49649092883&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49649092883&partnerID=8YFLogxK

U2 - 10.1117/1.2909671

DO - 10.1117/1.2909671

M3 - Article

C2 - 18465961

AN - SCOPUS:49649092883

SN - 1083-3668

VL - 13

JO - Journal of Biomedical Optics

JF - Journal of Biomedical Optics

IS - 2

M1 - 021112

ER -

Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this