Abstract
The changes in total reflection and transmission of porcine myocardium due to thermal coagulation were measured during tissue heating in a temperature-controlled water bath, at different temperature ranging between 54°-63°C. At 633 nm, the measurements yield a picture of continuous decrease in transmission and a peak with a subsequent fall (approximately 10% from the peak) in reflection measurements of the tissue during coagulation process. Utilizing these measurements and an inverse solution to the radiative transfer equation, the optical properties of tissue, absorption, μa, and effective scattering, μ′s= μs(l-g) were calculated. A one-dimensional diffusion approximation was used to demonstrate the effects of thermally induced changes in the optical properties of tissue on light distribution in tissue. The pattern of changes in μa and μ′s seen to indicate that several simultaneous rate processes may be responsible for tissue coagulation. A postulate is put forward to use one such rate process to characterize threshold thermal damage to porcine myocardium and the accompanying protein denaturation.
Original language | English (US) |
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Pages (from-to) | 172-179 |
Number of pages | 8 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 1425 |
DOIs | |
State | Published - 1991 |
Externally published | Yes |
Event | Proceedings of Diagnostic and Therapeutic Cardiovascular Interventions - Los Angeles, CA, USA Duration: Jan 20 1991 → Jan 22 1991 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering