Effect of Bombesin and Gastrin-Releasing Peptide on the Release of Gastric Inhibitory Polypeptide and Insulin in Rats

George H. Greeley, Alan Spannagel, John Trowbridge, James C. Thompson

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The objective of this study was to determine whether bombesin- or gastrin-releasing peptide-induced release of insulin occurs before or after the release of gastric inhibitory polypeptide (GIP) in rats. The present results demonstrate that GIP release occurs before insulin release and suggest that bombesin-like peptides and GIP interact to stimulate insulin secretion.

Original languageEnglish (US)
Pages (from-to)540-542
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume182
Issue number4
DOIs
StatePublished - Sep 1986
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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