Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention

Emanuele Nicastri; Gary Kobinger; Francesco Vairo; Chiara Montaldo; Leonard E.G. Mboera; Rashid Ansunama; Alimuddin Zumla; Giuseppe Ippolito

doi:10.1016/j.idc.2019.08.005

Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention

Emanuele Nicastri, Gary Kobinger, Francesco Vairo, Chiara Montaldo, Leonard E.G. Mboera, Rashid Ansunama, Alimuddin Zumla, Giuseppe Ippolito

Research output: Contribution to journal › Review article › peer-review

Abstract

Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. The emerging diagnostic technologies, rapid viral characterization, geospatial mapping of EVD transmission, and new treatments and vaccines are discussed.

Original language	English (US)
Pages (from-to)	953-976
Number of pages	24
Journal	Infectious disease clinics of North America
Volume	33
Issue number	4
DOIs	https://doi.org/10.1016/j.idc.2019.08.005
State	Published - Dec 2019
Externally published	Yes

Keywords

Diagnosis
Ebola
Ebola hemorrhagic fever
Ebola virus diseases
Epidemiology
Prevention
Treatment
Vaccines

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1016/j.idc.2019.08.005

Cite this

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title = "Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention",

abstract = "Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. The emerging diagnostic technologies, rapid viral characterization, geospatial mapping of EVD transmission, and new treatments and vaccines are discussed.",

keywords = "Diagnosis, Ebola, Ebola hemorrhagic fever, Ebola virus diseases, Epidemiology, Prevention, Treatment, Vaccines",

author = "Emanuele Nicastri and Gary Kobinger and Francesco Vairo and Chiara Montaldo and Mboera, {Leonard E.G.} and Rashid Ansunama and Alimuddin Zumla and Giuseppe Ippolito",

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year = "2019",

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doi = "10.1016/j.idc.2019.08.005",

language = "English (US)",

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T1 - Ebola Virus Disease

T2 - Epidemiology, Clinical Features, Management, and Prevention

AU - Nicastri, Emanuele

AU - Kobinger, Gary

AU - Vairo, Francesco

AU - Montaldo, Chiara

AU - Mboera, Leonard E.G.

AU - Ansunama, Rashid

AU - Zumla, Alimuddin

AU - Ippolito, Giuseppe

PY - 2019/12

Y1 - 2019/12

N2 - Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. The emerging diagnostic technologies, rapid viral characterization, geospatial mapping of EVD transmission, and new treatments and vaccines are discussed.

AB - Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. The emerging diagnostic technologies, rapid viral characterization, geospatial mapping of EVD transmission, and new treatments and vaccines are discussed.

KW - Diagnosis

KW - Ebola

KW - Ebola hemorrhagic fever

KW - Ebola virus diseases

KW - Epidemiology

KW - Prevention

KW - Treatment

KW - Vaccines

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SN - 0891-5520

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JO - Infectious disease clinics of North America

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ER -

Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention

Abstract

Keywords

ASJC Scopus subject areas

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