TY - JOUR
T1 - Early use of allograft skin
T2 - Are 3-day microbiologic cultures safe?
AU - Britton-Byrd, Benita W.
AU - Lynch, James P.
AU - Williamson, Stephen
AU - McCauley, Robert L.
PY - 2008/3
Y1 - 2008/3
N2 - BACKGROUND: Under the guidance of the American Association of Tissue Banks and the Food and Drug Administration, the use of allograft skin is safer than ever. In addition to the donor selection process and serology studies, current practice is to wait until 7 days of negative microbiologic cultures are completed before use. However, we have used 3 days of negative cultures in special cases as needed for clinical use. But how safe is this practice? METHODS: Between 2002 and 2003, 735 allograft skin donors were authorized for exceptional release. Exceptional release forms were signed by surgeons to document knowledge of the 3-day microbiologic cultures. RESULTS: Only three donors were recalled for positive cultures. The recall rate was 0.41%. CONCLUSIONS: The use of 3-day microbiologic cultures is 99.59% safe. Thus, the early use of allograft skin does not increase the chances of microbiologic contamination to patients.
AB - BACKGROUND: Under the guidance of the American Association of Tissue Banks and the Food and Drug Administration, the use of allograft skin is safer than ever. In addition to the donor selection process and serology studies, current practice is to wait until 7 days of negative microbiologic cultures are completed before use. However, we have used 3 days of negative cultures in special cases as needed for clinical use. But how safe is this practice? METHODS: Between 2002 and 2003, 735 allograft skin donors were authorized for exceptional release. Exceptional release forms were signed by surgeons to document knowledge of the 3-day microbiologic cultures. RESULTS: Only three donors were recalled for positive cultures. The recall rate was 0.41%. CONCLUSIONS: The use of 3-day microbiologic cultures is 99.59% safe. Thus, the early use of allograft skin does not increase the chances of microbiologic contamination to patients.
KW - Allograft skin
KW - Burns
KW - Microbiology cultures
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U2 - 10.1097/TA.0b013e318165bbf9
DO - 10.1097/TA.0b013e318165bbf9
M3 - Article
C2 - 18332829
AN - SCOPUS:40549100991
SN - 0022-5282
VL - 64
SP - 816
EP - 818
JO - Journal of Trauma - Injury, Infection and Critical Care
JF - Journal of Trauma - Injury, Infection and Critical Care
IS - 3
ER -