Early history of circular RNAs, children of splicing

Zvi Pasman, Mariano A. Garcia-Blanco

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


In this commentary we briefly summarize early work on circular RNAs derived from spliceosome mediated circularization. We highlight how this early work inspired work on the basic mechanisms of nuclear RNA splicing, the possible function of circular RNAs and the potential uses of circular RNAs as tools in biomedicine. Recent developments in the study of circular RNAs, summarized in this volume, have brought these questions back to the foreground.

Original languageEnglish (US)
Pages (from-to)975-977
Number of pages3
JournalRNA Biology
Issue number8
StatePublished - Aug 3 2017
Externally publishedYes


  • Circular RNA
  • Sry
  • exon circularization
  • splice site approximation
  • spliceosome mediated splicing

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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