Dupuytren's disease: History, diagnosis, and treatment

Robert B. Shaw, Alphonsus K.S. Chong, Andrew Zhang, Vincent R. Hentz, James Chang

Research output: Contribution to journalReview articlepeer-review

96 Scopus citations


LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Describe the clinical features of the disease. 2. Describe the pathoanatomical structures in Dupuytren's disease. 3. Outline the various factors associated with Dupuytren's disease. 4. Describe the modalities for surgical and nonsurgical treatment of the condition. 5. Outline recent biomolecular knowledge about the basis of Dupuytren's disease. SUMMARY: Dupuytren's disease is characterized by nodule formation and contracture of the palmar fascia, resulting in flexion deformity of the fingers and loss of hand function. The authors review the historical background, clinical features, and current therapy of Dupuytren's disease; preview treatment innovations; and present molecular data related to Dupuytren's disease. These new findings may improve screening for Dupuytren's disease and provide a better understanding of the disease's pathogenesis.

Original languageEnglish (US)
Pages (from-to)44e-54e
JournalPlastic and reconstructive surgery
Issue number3
StatePublished - Sep 2007
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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