Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Adam A. Dmytriw; Hamza Salim; Basel Musmar; Assala Aslan; Nicole M. Cancelliere; Rachel M. McLellan; Oktay Algin; Sherief Ghozy; Mahmoud Dibas; Sovann V. Lay; Adrien Guenego; Leonardo Renieri; Joseph Carnevale; Guillaume Saliou; Panagiotis Mastorakos; Kareem El Naamani; Eimad Shotar; Kevin Premat; Markus Möhlenbruch; Michael Kral; Omer Doron; Charlotte Chung; Mohamed M. Salem; Ivan Lylyk; Paul M. Foreman; Jay A. Vachhani; Hamza Shaikh; Vedran Župančić; Muhammad U. Hafeez; Joshua Catapano; Muhammad Waqas; Vincent M. Tutino; Mohamed K. Ibrahim; Marwa A. Mohammed; Cetin Imamoglu; Ahmet Bayrak; James D. Rabinov; Yifan Ren; Clemens M. Schirmer; Mariangela Piano; Anna L. Kühn; Caterina Michelozzi; Stéphanie Elens; Robert M. Starke; Ameer E. Hassan; Mark Ogilvie; Peter Sporns; Jesse Jones; Waleed Brinjikji; Marie T. Nawka; Marios Psychogios; Christian Ulfert; Jose Danilo Bengzon Diestro; Bryan Pukenas; Jan Karl Burkhardt; Thien Huynh; Juan Carlos Martinez-Gutierrez; Muhammed Amir Essibayi; Sunil A. Sheth; Gary Spiegel; Rabih Tawk; Boris Lubicz; Pietro Panni; Ajit S. Puri; Guglielmo Pero; Erez Nossek; Eytan Raz; Monika Killer-Oberfalzer; Christoph J. Griessenauer; Hamed Asadi; Adnan Siddiqui; Allan L. Brook; David Altschul; Andrew F. Ducruet; Felipe C. Albuquerque; Robert W. Regenhardt; Christopher J. Stapleton; Peter Kan; Vladimir Kalousek; Pedro Lylyk; Srikanth Boddu; Jared Knopman; Mohammad A. Aziz-Sultan; Stavropoula I. Tjoumakaris; Frédéric Clarençon; Nicola Limbucci; Hugo H. Cuellar-Saenz; Pascal M. Jabbour; Vitor Mendes Pereira; Aman B. Patel; Nimer Adeeb

doi:10.1007/s10143-024-02341-z

Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Adam A. Dmytriw, Hamza Salim, Basel Musmar, Assala Aslan, Nicole M. Cancelliere, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael KralOmer Doron, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, Cetin Imamoglu, Ahmet Bayrak, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer E. Hassan, Mark Ogilvie, Peter Sporns, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Jose Danilo Bengzon Diestro, Bryan Pukenas, Jan Karl Burkhardt, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L. Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, Nimer Adeeb

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms. Methods: A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture. Results: Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23). Conclusion: The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.

Original language	English (US)
Article number	116
Journal	Neurosurgical Review
Volume	47
Issue number	1
DOIs	https://doi.org/10.1007/s10143-024-02341-z
State	Published - Dec 2024

Keywords

Aneurysms
Intracranial
WEB
Woven EndoBridge, treatment

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1007/s10143-024-02341-z

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Dmytriw, A. A., Salim, H., Musmar, B., Aslan, A., Cancelliere, N. M., McLellan, R. M., Algin, O., Ghozy, S., Dibas, M., Lay, S. V., Guenego, A., Renieri, L., Carnevale, J., Saliou, G., Mastorakos, P., Naamani, K. E., Shotar, E., Premat, K., Möhlenbruch, M., ... Adeeb, N. (2024). Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis. Neurosurgical Review, 47(1), Article 116. https://doi.org/10.1007/s10143-024-02341-z

Dmytriw, AA, Salim, H, Musmar, B, Aslan, A, Cancelliere, NM, McLellan, RM, Algin, O, Ghozy, S, Dibas, M, Lay, SV, Guenego, A, Renieri, L, Carnevale, J, Saliou, G, Mastorakos, P, Naamani, KE, Shotar, E, Premat, K, Möhlenbruch, M, Kral, M, Doron, O, Chung, C, Salem, MM, Lylyk, I, Foreman, PM, Vachhani, JA, Shaikh, H, Župančić, V, Hafeez, MU, Catapano, J, Waqas, M, Tutino, VM, Ibrahim, MK, Mohammed, MA, Imamoglu, C, Bayrak, A, Rabinov, JD, Ren, Y, Schirmer, CM, Piano, M, Kühn, AL, Michelozzi, C, Elens, S, Starke, RM, Hassan, AE, Ogilvie, M, Sporns, P, Jones, J, Brinjikji, W, Nawka, MT, Psychogios, M, Ulfert, C, Diestro, JDB, Pukenas, B, Burkhardt, JK, Huynh, T, Martinez-Gutierrez, JC, Essibayi, MA, Sheth, SA, Spiegel, G, Tawk, R, Lubicz, B, Panni, P, Puri, AS, Pero, G, Nossek, E, Raz, E, Killer-Oberfalzer, M, Griessenauer, CJ, Asadi, H, Siddiqui, A, Brook, AL, Altschul, D, Ducruet, AF, Albuquerque, FC, Regenhardt, RW, Stapleton, CJ, Kan, P, Kalousek, V, Lylyk, P, Boddu, S, Knopman, J, Aziz-Sultan, MA, Tjoumakaris, SI, Clarençon, F, Limbucci, N, Cuellar-Saenz, HH, Jabbour, PM, Pereira, VM, Patel, AB & Adeeb, N 2024, 'Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis', Neurosurgical Review, vol. 47, no. 1, 116. https://doi.org/10.1007/s10143-024-02341-z

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title = "Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis",

abstract = "Background: The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms. Methods: A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture. Results: Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23). Conclusion: The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.",

keywords = "Aneurysms, Intracranial, WEB, Woven EndoBridge, treatment",

author = "Dmytriw, {Adam A.} and Hamza Salim and Basel Musmar and Assala Aslan and Cancelliere, {Nicole M.} and McLellan, {Rachel M.} and Oktay Algin and Sherief Ghozy and Mahmoud Dibas and Lay, {Sovann V.} and Adrien Guenego and Leonardo Renieri and Joseph Carnevale and Guillaume Saliou and Panagiotis Mastorakos and Naamani, {Kareem El} and Eimad Shotar and Kevin Premat and Markus M{\"o}hlenbruch and Michael Kral and Omer Doron and Charlotte Chung and Salem, {Mohamed M.} and Ivan Lylyk and Foreman, {Paul M.} and Vachhani, {Jay A.} and Hamza Shaikh and Vedran {\v Z}upan{\v c}i{\'c} and Hafeez, {Muhammad U.} and Joshua Catapano and Muhammad Waqas and Tutino, {Vincent M.} and Ibrahim, {Mohamed K.} and Mohammed, {Marwa A.} and Cetin Imamoglu and Ahmet Bayrak and Rabinov, {James D.} and Yifan Ren and Schirmer, {Clemens M.} and Mariangela Piano and K{\"u}hn, {Anna L.} and Caterina Michelozzi and St{\'e}phanie Elens and Starke, {Robert M.} and Hassan, {Ameer E.} and Mark Ogilvie and Peter Sporns and Jesse Jones and Waleed Brinjikji and Nawka, {Marie T.} and Marios Psychogios and Christian Ulfert and Diestro, {Jose Danilo Bengzon} and Bryan Pukenas and Burkhardt, {Jan Karl} and Thien Huynh and Martinez-Gutierrez, {Juan Carlos} and Essibayi, {Muhammed Amir} and Sheth, {Sunil A.} and Gary Spiegel and Rabih Tawk and Boris Lubicz and Pietro Panni and Puri, {Ajit S.} and Guglielmo Pero and Erez Nossek and Eytan Raz and Monika Killer-Oberfalzer and Griessenauer, {Christoph J.} and Hamed Asadi and Adnan Siddiqui and Brook, {Allan L.} and David Altschul and Ducruet, {Andrew F.} and Albuquerque, {Felipe C.} and Regenhardt, {Robert W.} and Stapleton, {Christopher J.} and Peter Kan and Vladimir Kalousek and Pedro Lylyk and Srikanth Boddu and Jared Knopman and Aziz-Sultan, {Mohammad A.} and Tjoumakaris, {Stavropoula I.} and Fr{\'e}d{\'e}ric Claren{\c c}on and Nicola Limbucci and Cuellar-Saenz, {Hugo H.} and Jabbour, {Pascal M.} and Pereira, {Vitor Mendes} and Patel, {Aman B.} and Nimer Adeeb",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.",

year = "2024",

month = dec,

doi = "10.1007/s10143-024-02341-z",

language = "English (US)",

volume = "47",

journal = "Neurosurgical Review",

issn = "0344-5607",

publisher = "Springer Verlag",

number = "1",

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TY - JOUR

T1 - Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms

T2 - A Propensity Score-Matched Analysis

AU - Dmytriw, Adam A.

AU - Salim, Hamza

AU - Musmar, Basel

AU - Aslan, Assala

AU - Cancelliere, Nicole M.

AU - McLellan, Rachel M.

AU - Algin, Oktay

AU - Ghozy, Sherief

AU - Dibas, Mahmoud

AU - Lay, Sovann V.

AU - Guenego, Adrien

AU - Renieri, Leonardo

AU - Carnevale, Joseph

AU - Saliou, Guillaume

AU - Mastorakos, Panagiotis

AU - Naamani, Kareem El

AU - Shotar, Eimad

AU - Premat, Kevin

AU - Möhlenbruch, Markus

AU - Kral, Michael

AU - Doron, Omer

AU - Chung, Charlotte

AU - Salem, Mohamed M.

AU - Lylyk, Ivan

AU - Foreman, Paul M.

AU - Vachhani, Jay A.

AU - Shaikh, Hamza

AU - Župančić, Vedran

AU - Hafeez, Muhammad U.

AU - Catapano, Joshua

AU - Waqas, Muhammad

AU - Tutino, Vincent M.

AU - Ibrahim, Mohamed K.

AU - Mohammed, Marwa A.

AU - Imamoglu, Cetin

AU - Bayrak, Ahmet

AU - Rabinov, James D.

AU - Ren, Yifan

AU - Schirmer, Clemens M.

AU - Piano, Mariangela

AU - Kühn, Anna L.

AU - Michelozzi, Caterina

AU - Elens, Stéphanie

AU - Starke, Robert M.

AU - Hassan, Ameer E.

AU - Ogilvie, Mark

AU - Sporns, Peter

AU - Jones, Jesse

AU - Brinjikji, Waleed

AU - Nawka, Marie T.

AU - Psychogios, Marios

AU - Ulfert, Christian

AU - Diestro, Jose Danilo Bengzon

AU - Pukenas, Bryan

AU - Burkhardt, Jan Karl

AU - Huynh, Thien

AU - Martinez-Gutierrez, Juan Carlos

AU - Essibayi, Muhammed Amir

AU - Sheth, Sunil A.

AU - Spiegel, Gary

AU - Tawk, Rabih

AU - Lubicz, Boris

AU - Panni, Pietro

AU - Puri, Ajit S.

AU - Pero, Guglielmo

AU - Nossek, Erez

AU - Raz, Eytan

AU - Killer-Oberfalzer, Monika

AU - Griessenauer, Christoph J.

AU - Asadi, Hamed

AU - Siddiqui, Adnan

AU - Brook, Allan L.

AU - Altschul, David

AU - Ducruet, Andrew F.

AU - Albuquerque, Felipe C.

AU - Regenhardt, Robert W.

AU - Stapleton, Christopher J.

AU - Kan, Peter

AU - Kalousek, Vladimir

AU - Lylyk, Pedro

AU - Boddu, Srikanth

AU - Knopman, Jared

AU - Aziz-Sultan, Mohammad A.

AU - Tjoumakaris, Stavropoula I.

AU - Clarençon, Frédéric

AU - Limbucci, Nicola

AU - Cuellar-Saenz, Hugo H.

AU - Jabbour, Pascal M.

AU - Pereira, Vitor Mendes

AU - Patel, Aman B.

AU - Adeeb, Nimer

N1 - Publisher Copyright: © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.

PY - 2024/12

Y1 - 2024/12

N2 - Background: The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms. Methods: A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture. Results: Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23). Conclusion: The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.

AB - Background: The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms. Methods: A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture. Results: Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23). Conclusion: The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.

KW - Aneurysms

KW - Intracranial

KW - WEB

KW - Woven EndoBridge, treatment

UR - http://www.scopus.com/inward/record.url?scp=85187828543&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85187828543&partnerID=8YFLogxK

U2 - 10.1007/s10143-024-02341-z

DO - 10.1007/s10143-024-02341-z

M3 - Article

C2 - 38483647

AN - SCOPUS:85187828543

SN - 0344-5607

VL - 47

JO - Neurosurgical Review

JF - Neurosurgical Review

IS - 1

M1 - 116

ER -

Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

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