Drug-Induced Hypokalaemia: A Cause for Concern

Gerald Isaac, O. Bryan Holland

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Drug-induced hypokalaemia is a widespread problem in the elderly that can be caused by many therapeutically useful substances, the most common of which are diuretics. In certain classes of patients (e.g. those with acute myocardial infarction, with congestive heart failure receiving digitalis, or with cirrhosis), iatrogenic hypokalaemia is an established risk factor. In patients with hypertension who have no underlying heart disease or liver disease, the use of diuretics may lead to worsened glucose tolerance and cardiac arrythmias. There is also evidence for an increased risk of sudden cardiac death.

Original languageEnglish (US)
Pages (from-to)35-41
Number of pages7
JournalDrugs & Aging
Issue number1
StatePublished - Jan 1992
Externally publishedYes

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Pharmacology (medical)


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