Diagnosis and management of Ebola samples in the laboratory

Marc Antoine de La Vega, Alexander Bello, Pascale Chaillet, Gary P. Kobinger

Research output: Contribution to journalReview articlepeer-review


The magnitude of the 2014–2016 West African Ebola virus outbreak has highlighted the importance of immediate and rapid deployment of control measures in affected areas. While many prophylactic and therapeutic options entered clinical trials in the past two years, larger use to impact on Ebola spread will not be possible until at least one product meets final approval by regulatory agencies. Control of the West African outbreak was achieved almost entirely by breaking chain of transmissions through case identification and specialized treatment, communication, safe burials and other proven methods. To achieve this in a timely manner, epidemiologists and medical teams are working in concert with laboratories to identify infected individuals and provide care within Ebola treatment units. Herein, we review an outbreak response workflow from the point of view of mobile laboratories and summarize methods that have been used by them during the West African Ebola virus outbreak of 2014–2016.

Original languageEnglish (US)
Pages (from-to)557-567
Number of pages11
JournalExpert Review of Anti-Infective Therapy
Issue number6
StatePublished - Jun 2 2016
Externally publishedYes


  • Ebola virus
  • diagnosis
  • laboratory
  • outbreak
  • point-of-care testing
  • sample management

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


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