Detecting laser induced thermal activity in tissue - a Doppler ultrasound approach

Hao Ying; Aamer Azeemi; Craig J. Hartley; Massoud Motamedi; Sohi Rastegar; Louis C. Sheppard

Detecting laser induced thermal activity in tissue - a Doppler ultrasound approach

Hao Ying, Aamer Azeemi, Craig J. Hartley, Massoud Motamedi, Sohi Rastegar, Louis C. Sheppard

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Abstract

There is a growing need for a real-time noninvasive technique to determine the extent and geometry of treated tissue during thermal therapy. We have developed an analog-digital hybrid system which measures the phase and amplitude of the ultrasonic echoes returned from a heated tissue at multiple depths. Two distinct types of echo modulations were observed in our in-vitro studies using beef muscle irradiated with an 810 nm diode laser. Type 1 modulation showed small and slow variations in amplitude and phase, whereas type 2 modulation demonstrated much larger and faster variations in both amplitude and phase. Our study suggests that type 1 modulation is consistent with tissue coagulation, whereas type 2 modulation is associated with tissue evaporation and explosive events.

Original language	English (US)
Pages (from-to)	1589-1592
Number of pages	4
Journal	Proceedings of the IEEE Ultrasonics Symposium
Volume	2
State	Published - 1995
Event	Proceedings of the 1995 IEEE Ultrasonics Symposium. Part 1 (of 2) - Seattle, WA, USA Duration: Nov 7 1995 → Nov 10 1995

ASJC Scopus subject areas

Acoustics and Ultrasonics

Cite this

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title = "Detecting laser induced thermal activity in tissue - a Doppler ultrasound approach",

abstract = "There is a growing need for a real-time noninvasive technique to determine the extent and geometry of treated tissue during thermal therapy. We have developed an analog-digital hybrid system which measures the phase and amplitude of the ultrasonic echoes returned from a heated tissue at multiple depths. Two distinct types of echo modulations were observed in our in-vitro studies using beef muscle irradiated with an 810 nm diode laser. Type 1 modulation showed small and slow variations in amplitude and phase, whereas type 2 modulation demonstrated much larger and faster variations in both amplitude and phase. Our study suggests that type 1 modulation is consistent with tissue coagulation, whereas type 2 modulation is associated with tissue evaporation and explosive events.",

author = "Hao Ying and Aamer Azeemi and Hartley, {Craig J.} and Massoud Motamedi and Sohi Rastegar and Sheppard, {Louis C.}",

year = "1995",

language = "English (US)",

volume = "2",

pages = "1589--1592",

journal = "Proceedings of the IEEE Ultrasonics Symposium",

issn = "1051-0117",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

note = "Proceedings of the 1995 IEEE Ultrasonics Symposium. Part 1 (of 2) ; Conference date: 07-11-1995 Through 10-11-1995",

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TY - JOUR

T1 - Detecting laser induced thermal activity in tissue - a Doppler ultrasound approach

AU - Ying, Hao

AU - Azeemi, Aamer

AU - Hartley, Craig J.

AU - Motamedi, Massoud

AU - Rastegar, Sohi

AU - Sheppard, Louis C.

PY - 1995

Y1 - 1995

N2 - There is a growing need for a real-time noninvasive technique to determine the extent and geometry of treated tissue during thermal therapy. We have developed an analog-digital hybrid system which measures the phase and amplitude of the ultrasonic echoes returned from a heated tissue at multiple depths. Two distinct types of echo modulations were observed in our in-vitro studies using beef muscle irradiated with an 810 nm diode laser. Type 1 modulation showed small and slow variations in amplitude and phase, whereas type 2 modulation demonstrated much larger and faster variations in both amplitude and phase. Our study suggests that type 1 modulation is consistent with tissue coagulation, whereas type 2 modulation is associated with tissue evaporation and explosive events.

AB - There is a growing need for a real-time noninvasive technique to determine the extent and geometry of treated tissue during thermal therapy. We have developed an analog-digital hybrid system which measures the phase and amplitude of the ultrasonic echoes returned from a heated tissue at multiple depths. Two distinct types of echo modulations were observed in our in-vitro studies using beef muscle irradiated with an 810 nm diode laser. Type 1 modulation showed small and slow variations in amplitude and phase, whereas type 2 modulation demonstrated much larger and faster variations in both amplitude and phase. Our study suggests that type 1 modulation is consistent with tissue coagulation, whereas type 2 modulation is associated with tissue evaporation and explosive events.

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M3 - Conference article

AN - SCOPUS:0029453512

SN - 1051-0117

VL - 2

SP - 1589

EP - 1592

JO - Proceedings of the IEEE Ultrasonics Symposium

JF - Proceedings of the IEEE Ultrasonics Symposium

T2 - Proceedings of the 1995 IEEE Ultrasonics Symposium. Part 1 (of 2)

Y2 - 7 November 1995 through 10 November 1995

ER -

Detecting laser induced thermal activity in tissue - a Doppler ultrasound approach

Abstract

ASJC Scopus subject areas

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