Degradation of ribosomal RNA during chicken lens development

William F. Zapisek; John Papaconstantinou

doi:10.1016/0005-2787(73)90233-5

Degradation of ribosomal RNA during chicken lens development

William F. Zapisek, John Papaconstantinou

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.

Original language	English (US)
Pages (from-to)	603-611
Number of pages	9
Journal	BBA Section Nucleic Acids And Protein Synthesis
Volume	299
Issue number	4
DOIs	https://doi.org/10.1016/0005-2787(73)90233-5
State	Published - Apr 11 1973
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Degradation of ribosomal RNA during chicken lens development",

abstract = "During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.",

author = "Zapisek, {William F.} and John Papaconstantinou",

note = "Funding Information: This research was jointly sponsored by Oak Ridge Associated Universities (O.R.A.U.), and the United States Atomic Energy Commission under contract with the Union Carbide Corporation.",

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doi = "10.1016/0005-2787(73)90233-5",

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T1 - Degradation of ribosomal RNA during chicken lens development

AU - Zapisek, William F.

AU - Papaconstantinou, John

N1 - Funding Information: This research was jointly sponsored by Oak Ridge Associated Universities (O.R.A.U.), and the United States Atomic Energy Commission under contract with the Union Carbide Corporation.

PY - 1973/4/11

Y1 - 1973/4/11

N2 - During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.

AB - During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.

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JO - BBA Section Nucleic Acids And Protein Synthesis

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ER -

Degradation of ribosomal RNA during chicken lens development

Abstract

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