TY - JOUR
T1 - Dakin's Solution
T2 - “One of the most important and far-reaching contributions to the armamentarium of the surgeons”
AU - Georgiadis, Jeremias
AU - Nascimento, Vanessa B.
AU - Donat, Catherine
AU - Okereke, Ikenna
AU - Shoja, Mohammadali M.
N1 - Publisher Copyright:
© 2018 Elsevier Ltd and ISBI
PY - 2019/11
Y1 - 2019/11
N2 - Henry Drysdale Dakin is a notable person in the history of surgery, wound care, military medicine and infectious disease control. Dakin is an exemplar scientist who in the midst of war forged an international collaboration with scientists in multiple fields to create and universalize an antiseptic utopia, which saved thousands lives during World War I, remarkably diminished functional disabilities from wounds and continues to be a “far-reaching armamentarium” of the surgeons and wound care specialists around the globe. Dakin investigated over 200 different antiseptic substances to finally conclude that a 0.5% buffered sodium hypochlorite solution satisfies his criteria for an ideal antiseptic. The only potential limitation was that the germicidal property of the solution was short lived, which meant the solution had to be used continuously or repeatedly delivered into wounds. Dakin's solution, still in use by modern wound care specialists around the globe, has laid the foundation for wound care management as we know it today. Nevertheless, Dakin contributed more to science than just his solution. In this article, Dakin's life story, his unique scientific career and his contributions to surgical literature are explored. The article also illustrates how a wartime necessity resulted in a medical discovery that is still in use to date.
AB - Henry Drysdale Dakin is a notable person in the history of surgery, wound care, military medicine and infectious disease control. Dakin is an exemplar scientist who in the midst of war forged an international collaboration with scientists in multiple fields to create and universalize an antiseptic utopia, which saved thousands lives during World War I, remarkably diminished functional disabilities from wounds and continues to be a “far-reaching armamentarium” of the surgeons and wound care specialists around the globe. Dakin investigated over 200 different antiseptic substances to finally conclude that a 0.5% buffered sodium hypochlorite solution satisfies his criteria for an ideal antiseptic. The only potential limitation was that the germicidal property of the solution was short lived, which meant the solution had to be used continuously or repeatedly delivered into wounds. Dakin's solution, still in use by modern wound care specialists around the globe, has laid the foundation for wound care management as we know it today. Nevertheless, Dakin contributed more to science than just his solution. In this article, Dakin's life story, his unique scientific career and his contributions to surgical literature are explored. The article also illustrates how a wartime necessity resulted in a medical discovery that is still in use to date.
KW - Antiseptic
KW - Burn
KW - History
KW - Military Medicine
KW - Wound
UR - http://www.scopus.com/inward/record.url?scp=85058931040&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85058931040&partnerID=8YFLogxK
U2 - 10.1016/j.burns.2018.12.001
DO - 10.1016/j.burns.2018.12.001
M3 - Review article
C2 - 30591251
AN - SCOPUS:85058931040
SN - 0305-4179
VL - 45
SP - 1509
EP - 1517
JO - Burns
JF - Burns
IS - 7
ER -