Cyst(e)ine measurements during total parenteral nutrition

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8 Scopus citations


Using a method that measures plasma protein-bound 1/2 cystine, plasma free cyst(e)ine, and urine free cyst(e)ine, we have observed that infants receiving total parenteral nutrition supplemented with cysteine-HCl have significantly higher plasma and urine free cyst(e)ine concentrations (11.3 ± 3.4 μm/dl and 47.2 ± 24.0 μm/dl x̄ ± SD) than when 1/2 cystine concentrations are measured by automated amino acid analysis (7.4 ± 2.0 μm/dl, plasma and 25.0 ± 7.0 μm/dl, urine). These data suggest that both the sulfhydryl and disulfide form of cyst(e)ine must be measured to assess the effect of cysteine-HCl supplemented total parenteral nutrition.

Original languageEnglish (US)
Pages (from-to)188-191
Number of pages4
JournalAmerican Journal of Clinical Nutrition
Issue number2
StatePublished - 1983

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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