TY - JOUR
T1 - Correlation of magnetic resonance imaging and pathologic size of infiltrating lobular carcinoma of the breast
AU - Kepple, Julie
AU - Layeeque, Rakhshanda
AU - Klimberg, V. Suzanne
AU - Harms, Steven
AU - Siegel, Eric
AU - Korourian, Soheila
AU - Gusmano, Flavia
AU - Henry-Tillman, Ronda S.
N1 - Funding Information:
Supported by the Susan G. Komen Breast Cancer Clinical Fellowship and the Virginia Clinton Kelley/Fashion Footwear Association of New York Breast Cancer Research Fellowship (J.K.).
PY - 2005/10
Y1 - 2005/10
N2 - Background: Determining the extent of infiltrating lobular carcinoma (ILCA) in the breast is difficult. This study was designed to determine if the size of ILCA on magnetic resonance imaging (MRI) correlated with final pathology. Methods: Retrospective study of patients between 1998 and 2004, who were evaluated for extent of ILCA prior to definitive treatment, was conducted. Demographic data and radiology and pathology results were obtained. Spearman correlation coefficient was used. Results: Twenty-nine patients (median age 62 years) had MRI of breast. Fourteen patients (48%) had contralateral MRIs; 13 (45%) normal; 1 (8%) prompted core biopsy; 6 of 13 patients underwent contralateral mastectomies, which were benign. The distribution of tumor size was: T1 = 15 (52%); T2 = 7 (24%); T3 = 5 (17%); T4 = 2 (7%). Spearman correlation coefficient between tumor size on ultrasound and MRI with pathology was .19 (P = .5) and .88 (P < .001), respectively. Conclusion: MRI provided superior correlation between tumor size and pathology.
AB - Background: Determining the extent of infiltrating lobular carcinoma (ILCA) in the breast is difficult. This study was designed to determine if the size of ILCA on magnetic resonance imaging (MRI) correlated with final pathology. Methods: Retrospective study of patients between 1998 and 2004, who were evaluated for extent of ILCA prior to definitive treatment, was conducted. Demographic data and radiology and pathology results were obtained. Spearman correlation coefficient was used. Results: Twenty-nine patients (median age 62 years) had MRI of breast. Fourteen patients (48%) had contralateral MRIs; 13 (45%) normal; 1 (8%) prompted core biopsy; 6 of 13 patients underwent contralateral mastectomies, which were benign. The distribution of tumor size was: T1 = 15 (52%); T2 = 7 (24%); T3 = 5 (17%); T4 = 2 (7%). Spearman correlation coefficient between tumor size on ultrasound and MRI with pathology was .19 (P = .5) and .88 (P < .001), respectively. Conclusion: MRI provided superior correlation between tumor size and pathology.
KW - Breast cancer
KW - Correlation
KW - Infiltrating lobular carcinoma
KW - Magnetic resonance imaging
KW - Staging
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U2 - 10.1016/j.amjsurg.2005.06.028
DO - 10.1016/j.amjsurg.2005.06.028
M3 - Article
C2 - 16164936
AN - SCOPUS:24944447172
SN - 0002-9610
VL - 190
SP - 623
EP - 627
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 4
ER -