Coronary Physiology Assessment for the Diagnosis and Treatment of Stable Ischemic Heart Disease

Ali E. Denktas; David Paniagua; Hani Jneid

doi:10.1007/s11883-016-0613-2

Coronary Physiology Assessment for the Diagnosis and Treatment of Stable Ischemic Heart Disease

Ali E. Denktas, David Paniagua, Hani Jneid

Research output: Contribution to journal › Review article › peer-review

Abstract

Coronary artery disease is the most prevalent cardiovascular disease in the USA. In the majority of settings, percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) reduces angina and improves quality of life; however, it does not improve survival and is associated with infrequent but serious complications. Selection of appropriate patients and coronary lesions for revascularization with PCI is crucial to maximize the benefit-to-risk ratio. The assessment of the hemodynamic significance of intermediate coronary lesions has been shown to improve outcomes and reduce healthcare costs. The current review summarizes the existing evidence regarding the physiological assessment of coronary lesions, with emphasis on fractional flow reserve, the most common invasive hemodynamic assessment modality.

Original language	English (US)
Article number	62
Journal	Current Atherosclerosis Reports
Volume	18
Issue number	10
DOIs	https://doi.org/10.1007/s11883-016-0613-2
State	Published - Oct 1 2016
Externally published	Yes

Keywords

Angiography
Catheterization
Coronary
Coronary artery disease
Fractional flow reserve
Physiology
Stenosis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1007/s11883-016-0613-2

Cite this

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title = "Coronary Physiology Assessment for the Diagnosis and Treatment of Stable Ischemic Heart Disease",

abstract = "Coronary artery disease is the most prevalent cardiovascular disease in the USA. In the majority of settings, percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) reduces angina and improves quality of life; however, it does not improve survival and is associated with infrequent but serious complications. Selection of appropriate patients and coronary lesions for revascularization with PCI is crucial to maximize the benefit-to-risk ratio. The assessment of the hemodynamic significance of intermediate coronary lesions has been shown to improve outcomes and reduce healthcare costs. The current review summarizes the existing evidence regarding the physiological assessment of coronary lesions, with emphasis on fractional flow reserve, the most common invasive hemodynamic assessment modality.",

keywords = "Angiography, Catheterization, Coronary, Coronary artery disease, Fractional flow reserve, Physiology, Stenosis",

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AU - Denktas, Ali E.

AU - Paniagua, David

AU - Jneid, Hani

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Y1 - 2016/10/1

N2 - Coronary artery disease is the most prevalent cardiovascular disease in the USA. In the majority of settings, percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) reduces angina and improves quality of life; however, it does not improve survival and is associated with infrequent but serious complications. Selection of appropriate patients and coronary lesions for revascularization with PCI is crucial to maximize the benefit-to-risk ratio. The assessment of the hemodynamic significance of intermediate coronary lesions has been shown to improve outcomes and reduce healthcare costs. The current review summarizes the existing evidence regarding the physiological assessment of coronary lesions, with emphasis on fractional flow reserve, the most common invasive hemodynamic assessment modality.

AB - Coronary artery disease is the most prevalent cardiovascular disease in the USA. In the majority of settings, percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) reduces angina and improves quality of life; however, it does not improve survival and is associated with infrequent but serious complications. Selection of appropriate patients and coronary lesions for revascularization with PCI is crucial to maximize the benefit-to-risk ratio. The assessment of the hemodynamic significance of intermediate coronary lesions has been shown to improve outcomes and reduce healthcare costs. The current review summarizes the existing evidence regarding the physiological assessment of coronary lesions, with emphasis on fractional flow reserve, the most common invasive hemodynamic assessment modality.

KW - Angiography

KW - Catheterization

KW - Coronary

KW - Coronary artery disease

KW - Fractional flow reserve

KW - Physiology

KW - Stenosis

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Coronary Physiology Assessment for the Diagnosis and Treatment of Stable Ischemic Heart Disease

Abstract

Keywords

ASJC Scopus subject areas

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