Configurational entropy of native proteins

M. Karplus, T. Ichiye, B. M. Pettitt

Research output: Contribution to journalArticlepeer-review

165 Scopus citations


Simulations of the residual configurational entropy of a protein in the native state suggest that it is nearly an order of magnitude larger than the entropy of denaturation. The implications of this result are discussed.

Original languageEnglish (US)
Pages (from-to)1083-1085
Number of pages3
JournalBiophysical journal
Issue number6
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics


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