COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27™/ColonRing™

A. D'Hoore; M. R. Albert; S. M. Cohen; F. Herbst; I. Matter; K. Van Der Speeten; J. Dominguez; H. Rutten; J. P. Muldoon; O. Bardakcioglu; A. J. Senagore; R. Ruppert; S. Mills; M. J. Stamos; L. Påhlman; E. Choman; S. D. Wexner; behalf of the COMPRES collaborative study group On behalf of the COMPRES collaborative study group

doi:10.1111/codi.12884

COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27^™/ColonRing^™

A. D'Hoore, M. R. Albert, S. M. Cohen, F. Herbst, I. Matter, K. Van Der Speeten, J. Dominguez, H. Rutten, J. P. Muldoon, O. Bardakcioglu, A. J. Senagore, R. Ruppert, S. Mills, M. J. Stamos, L. Påhlman, E. Choman, S. D. Wexner, behalf of the COMPRES collaborative study group On behalf of the COMPRES collaborative study group

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing^™ in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing^™ with conventional stapling is needed.

Original language	English (US)
Pages (from-to)	522-529
Number of pages	8
Journal	Colorectal Disease
Volume	17
Issue number	6
DOIs	https://doi.org/10.1111/codi.12884
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Anastomotic leakage
Compression anastomosis
Low anterior resection

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.1111/codi.12884

Cite this

D'Hoore, A., Albert, M. R., Cohen, S. M., Herbst, F., Matter, I., Van Der Speeten, K., Dominguez, J., Rutten, H., Muldoon, J. P., Bardakcioglu, O., Senagore, A. J., Ruppert, R., Mills, S., Stamos, M. J., Påhlman, L., Choman, E., Wexner, S. D., & On behalf of the COMPRES collaborative study group, B. O. T. COMPRES. C. S. G. (2015). COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27^™/ColonRing^™. Colorectal Disease, 17(6), 522-529. https://doi.org/10.1111/codi.12884

D'Hoore, A, Albert, MR, Cohen, SM, Herbst, F, Matter, I, Van Der Speeten, K, Dominguez, J, Rutten, H, Muldoon, JP, Bardakcioglu, O, Senagore, AJ, Ruppert, R, Mills, S, Stamos, MJ, Påhlman, L, Choman, E, Wexner, SD & On behalf of the COMPRES collaborative study group, BOTCOMPRESCSG 2015, 'COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27^™/ColonRing^™', Colorectal Disease, vol. 17, no. 6, pp. 522-529. https://doi.org/10.1111/codi.12884

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title = "COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27{\texttrademark}/ColonRing{\texttrademark}",

abstract = "Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing{\texttrademark} in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing{\texttrademark} with conventional stapling is needed.",

keywords = "Anastomotic leakage, Compression anastomosis, Low anterior resection",

author = "A. D'Hoore and Albert, {M. R.} and Cohen, {S. M.} and F. Herbst and I. Matter and {Van Der Speeten}, K. and J. Dominguez and H. Rutten and Muldoon, {J. P.} and O. Bardakcioglu and Senagore, {A. J.} and R. Ruppert and S. Mills and Stamos, {M. J.} and L. P{\aa}hlman and E. Choman and Wexner, {S. D.} and {On behalf of the COMPRES collaborative study group}, {behalf of the COMPRES collaborative study group}",

note = "Publisher Copyright: {\textcopyright} 2015 The Association of Coloproctology of Great Britain and Ireland 17 6 June 2015 10.1111/codi.12884 Original Article Original Articles General Colorectal Disease {\textcopyright} 2014 The Association of Coloproctology of Great Britain and Ireland.",

year = "2015",

month = jun,

day = "1",

doi = "10.1111/codi.12884",

language = "English (US)",

volume = "17",

pages = "522--529",

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T2 - A prospective postmarketing evaluation of the compression anastomosis ring CAR 27™/ColonRing™

AU - D'Hoore, A.

AU - Albert, M. R.

AU - Cohen, S. M.

AU - Herbst, F.

AU - Matter, I.

AU - Van Der Speeten, K.

AU - Dominguez, J.

AU - Rutten, H.

AU - Muldoon, J. P.

AU - Bardakcioglu, O.

AU - Senagore, A. J.

AU - Ruppert, R.

AU - Mills, S.

AU - Stamos, M. J.

AU - Påhlman, L.

AU - Choman, E.

AU - Wexner, S. D.

AU - On behalf of the COMPRES collaborative study group, behalf of the COMPRES collaborative study group

N1 - Publisher Copyright: © 2015 The Association of Coloproctology of Great Britain and Ireland 17 6 June 2015 10.1111/codi.12884 Original Article Original Articles General Colorectal Disease © 2014 The Association of Coloproctology of Great Britain and Ireland.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing™ in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing™ with conventional stapling is needed.

AB - Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing™ in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing™ with conventional stapling is needed.

KW - Anastomotic leakage

KW - Compression anastomosis

KW - Low anterior resection

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