Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY

Guillermo Gomez; Vidyavathi Udupi; George H. Greeley

doi:10.3181/00379727-215-44123

Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY

Guillermo Gomez, Vidyavathi Udupi, George H. Greeley

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) end somatostatin (SRIF) (400 pmol/kg/hr) on food- induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.

Original language	English (US)
Pages (from-to)	165-167
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	215
Issue number	2
DOIs	https://doi.org/10.3181/00379727-215-44123
State	Published - Jun 1997
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.3181/00379727-215-44123

Cite this

@article{30b33915a93d4d0da0dd873e7e86d07a,

title = "Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY",

abstract = "The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) end somatostatin (SRIF) (400 pmol/kg/hr) on food- induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.",

author = "Guillermo Gomez and Vidyavathi Udupi and Greeley, {George H.}",

note = "Funding Information: To whom requests for reprints should be addressed at Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555-0725. This work was supported by funds from the National Institutes of Health (POI DK35608) and the National Science Foundation (IBN 9506305). 6 1997 215 2 165 167 ",

year = "1997",

month = jun,

doi = "10.3181/00379727-215-44123",

language = "English (US)",

volume = "215",

pages = "165--167",

journal = "Proceedings of the Society for Experimental Biology and Medicine",

issn = "0037-9727",

publisher = "Frontiers Media SA",

number = "2",

}

TY - JOUR

T1 - Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY

AU - Gomez, Guillermo

AU - Udupi, Vidyavathi

AU - Greeley, George H.

N1 - Funding Information: To whom requests for reprints should be addressed at Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555-0725. This work was supported by funds from the National Institutes of Health (POI DK35608) and the National Science Foundation (IBN 9506305). 6 1997 215 2 165 167

PY - 1997/6

Y1 - 1997/6

N2 - The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) end somatostatin (SRIF) (400 pmol/kg/hr) on food- induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.

AB - The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) end somatostatin (SRIF) (400 pmol/kg/hr) on food- induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.

UR - http://www.scopus.com/inward/record.url?scp=0031009737&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031009737&partnerID=8YFLogxK

U2 - 10.3181/00379727-215-44123

DO - 10.3181/00379727-215-44123

M3 - Article

C2 - 9160043

AN - SCOPUS:0031009737

SN - 0037-9727

VL - 215

SP - 165

EP - 167

JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

IS - 2

ER -

Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this