TY - JOUR
T1 - Community preparedness for HIV vaccine trials in the Democratic Republic of Congo
AU - Olin, John
AU - Kokolamami, Jacques
AU - Lepira, Francois B.
AU - Mwandagalirwa, Kashamuka
AU - Mupenda, Bavon
AU - Ndongala, Michel Lubaki
AU - Maman, Suzanne
AU - Bollinger, Robert
AU - Nachega, Jean
AU - Mokili, John
PY - 2006/11
Y1 - 2006/11
N2 - This paper reports on an assessment of community preparedness for HIV vaccine trials in the Democratic Republic of Congo. Formative research was conducted in the capital city of Kinshasa during the period October 2003 to March 2004 to answer questions pertinent to planning trials of a preventive HIV vaccine and to identify related issues. Twenty-seven in-depth interviews and two focus groups were held with potential trial participants and community leaders. Data was collected on the subjects of vaccines, HIV/AIDS and sexual behaviour, and an HIV vaccine. The study also sought to identify factors that motivate a person to volunteer for a vaccine trial or which are disincentives to participation, along with preparedness of the larger community for trials. Personal concerns for health and for the impact of the epidemic on families and country were common motivations for participation. The danger of an experimental vaccine and the stigma of a positive HIV antibody test as the result of vaccination are major concerns and disincentives. The health, educational, and local non-governmental sectors are identified as having important roles to play in assuring preparedness for trials, although significant challenges exist to achieving community preparedness.
AB - This paper reports on an assessment of community preparedness for HIV vaccine trials in the Democratic Republic of Congo. Formative research was conducted in the capital city of Kinshasa during the period October 2003 to March 2004 to answer questions pertinent to planning trials of a preventive HIV vaccine and to identify related issues. Twenty-seven in-depth interviews and two focus groups were held with potential trial participants and community leaders. Data was collected on the subjects of vaccines, HIV/AIDS and sexual behaviour, and an HIV vaccine. The study also sought to identify factors that motivate a person to volunteer for a vaccine trial or which are disincentives to participation, along with preparedness of the larger community for trials. Personal concerns for health and for the impact of the epidemic on families and country were common motivations for participation. The danger of an experimental vaccine and the stigma of a positive HIV antibody test as the result of vaccination are major concerns and disincentives. The health, educational, and local non-governmental sectors are identified as having important roles to play in assuring preparedness for trials, although significant challenges exist to achieving community preparedness.
KW - Clinical trials
KW - Community preparedness
KW - HIV/AIDS
KW - Stigma
KW - Vaccine
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U2 - 10.1080/13691050600888434
DO - 10.1080/13691050600888434
M3 - Article
C2 - 17050384
AN - SCOPUS:33750018130
SN - 1369-1058
VL - 8
SP - 529
EP - 544
JO - Culture, Health and Sexuality
JF - Culture, Health and Sexuality
IS - 6
ER -