Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome: A Case Report

Theodore Zhang; M. Brent Price; Nicole Bravo; Joshua A. Villarreal; Michael L. Kueht; John Moore Vierling; Ronald Cotton; Thao Galvan; Christine Ann O'Mahony; John A. Goss; Abbas Rana

doi:10.1016/j.transproceed.2020.02.154

Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome: A Case Report

Theodore Zhang, M. Brent Price, Nicole Bravo, Joshua A. Villarreal, Michael L. Kueht, John Moore Vierling, Ronald Cotton, Thao Galvan, Christine Ann O'Mahony, John A. Goss, Abbas Rana

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Reports on the long-term outcomes and immunosuppressive regimens of multiorgan transplant patients are limited. Here, we describe a patient with cystic fibrosis complicated by multiorgan failure who was successfully treated with combined liver lung transplant and delayed kidney transplant, resulting in excellent outcomes. Delayed kidney transplant was done to reduce the operative stress of a single procedure, giving time for adequate resuscitation and weaning from vasopressors. Our patient's postoperative course was complicated by post-transplant lymphoproliferative disease, which was successfully treated with rituximab and reduced dosages of immunosuppression.

Original language	English (US)
Pages (from-to)	2824-2826
Number of pages	3
Journal	Transplantation proceedings
Volume	52
Issue number	9
DOIs	https://doi.org/10.1016/j.transproceed.2020.02.154
State	Published - Nov 2020
Externally published	Yes

ASJC Scopus subject areas

Surgery
Transplantation

Access to Document

10.1016/j.transproceed.2020.02.154

Cite this

Zhang, T., Price, M. B., Bravo, N., Villarreal, J. A., Kueht, M. L., Vierling, J. M., Cotton, R., Galvan, T., O'Mahony, C. A., Goss, J. A., & Rana, A. (2020). Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome: A Case Report. Transplantation proceedings, 52(9), 2824-2826. https://doi.org/10.1016/j.transproceed.2020.02.154

@article{5d181b8e37b34f768991f529969cfd34,

title = "Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome: A Case Report",

abstract = "Reports on the long-term outcomes and immunosuppressive regimens of multiorgan transplant patients are limited. Here, we describe a patient with cystic fibrosis complicated by multiorgan failure who was successfully treated with combined liver lung transplant and delayed kidney transplant, resulting in excellent outcomes. Delayed kidney transplant was done to reduce the operative stress of a single procedure, giving time for adequate resuscitation and weaning from vasopressors. Our patient's postoperative course was complicated by post-transplant lymphoproliferative disease, which was successfully treated with rituximab and reduced dosages of immunosuppression.",

author = "Theodore Zhang and Price, {M. Brent} and Nicole Bravo and Villarreal, {Joshua A.} and Kueht, {Michael L.} and Vierling, {John Moore} and Ronald Cotton and Thao Galvan and O'Mahony, {Christine Ann} and Goss, {John A.} and Abbas Rana",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = nov,

doi = "10.1016/j.transproceed.2020.02.154",

language = "English (US)",

volume = "52",

pages = "2824--2826",

journal = "Transplantation proceedings",

issn = "0041-1345",

publisher = "Elsevier USA",

number = "9",

}

TY - JOUR

T1 - Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome

T2 - A Case Report

AU - Zhang, Theodore

AU - Price, M. Brent

AU - Bravo, Nicole

AU - Villarreal, Joshua A.

AU - Kueht, Michael L.

AU - Vierling, John Moore

AU - Cotton, Ronald

AU - Galvan, Thao

AU - O'Mahony, Christine Ann

AU - Goss, John A.

AU - Rana, Abbas

PY - 2020/11

Y1 - 2020/11

N2 - Reports on the long-term outcomes and immunosuppressive regimens of multiorgan transplant patients are limited. Here, we describe a patient with cystic fibrosis complicated by multiorgan failure who was successfully treated with combined liver lung transplant and delayed kidney transplant, resulting in excellent outcomes. Delayed kidney transplant was done to reduce the operative stress of a single procedure, giving time for adequate resuscitation and weaning from vasopressors. Our patient's postoperative course was complicated by post-transplant lymphoproliferative disease, which was successfully treated with rituximab and reduced dosages of immunosuppression.

AB - Reports on the long-term outcomes and immunosuppressive regimens of multiorgan transplant patients are limited. Here, we describe a patient with cystic fibrosis complicated by multiorgan failure who was successfully treated with combined liver lung transplant and delayed kidney transplant, resulting in excellent outcomes. Delayed kidney transplant was done to reduce the operative stress of a single procedure, giving time for adequate resuscitation and weaning from vasopressors. Our patient's postoperative course was complicated by post-transplant lymphoproliferative disease, which was successfully treated with rituximab and reduced dosages of immunosuppression.

UR - http://www.scopus.com/inward/record.url?scp=85084410446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85084410446&partnerID=8YFLogxK

U2 - 10.1016/j.transproceed.2020.02.154

DO - 10.1016/j.transproceed.2020.02.154

M3 - Article

C2 - 32389488

AN - SCOPUS:85084410446

SN - 0041-1345

VL - 52

SP - 2824

EP - 2826

JO - Transplantation proceedings

JF - Transplantation proceedings

IS - 9

ER -

Combined Lung-Liver and Delayed Kidney Transplantation for Cystic Fibrosis Clinical Approach and Outcome: A Case Report

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this