Co-infections with hepatitis B and C viruses in human immunodeficiency virus-infected patients in Morocco

K. Rebbani, A. Ouladlahsen, A. Bensghir, A. Akil, H. Lamdini, H. Issouf, I. Brahim, B. Kitab, F. Z. Fakhir, L. Wakrim, K. Marhoum El Filali, H. Himmich, S. Ezzikouri, S. Benjelloun

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are major public health concerns. We aimed to determine the prevalence of HBV and HCV infections among HIV-infected patients, and to identify the main circulating hepatitis strains in Morocco. The study was carried out in 503 HIV-infected patients. Our survey indicated that the prevalence of HIV/hepatitis co-infection was 10.6%; 5.2% of patients were HBV surface antigen positive, and 5.4% of patients were anti-HCV positive. Among the HBV surface antigen-positive group, HBV DNA sequencing identified exclusively genotype D (D1: 26.7%; D7: 73.3%) in accordance with what is found in the general population. In contrast, sequencing of HCV isolates produced an unusual subtype distribution with a decreasing order of prevalence: 1a, 3a (both 23.5%), 1b, 4a (both 17.6%), 1c (11.8%) and 6h (6%).

Original languageEnglish (US)
Pages (from-to)E454-E457
JournalClinical Microbiology and Infection
Volume19
Issue number10
DOIs
StatePublished - Oct 2013
Externally publishedYes

Keywords

  • Chronic hepatitis
  • Co-infection
  • Genotype
  • Human immunodeficiency virus
  • Prevalence

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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