Abstract
Monitoring of cerebral venous oxygenation is critically important for management of patients with traumatic brain injury and cardiac surgery patients. At present, there is no technique for noninvasive, accurate monitoring of this important physiologic parameter. We built a compact optoacoustic system for noninvasive, accurate cerebral venous oxygenation monitoring using a novel optoacoustic probe and algorithm that allow for direct probing of sagittal sinus blood with minimal signal contamination from other tissues. We tested the system in large animal and clinical studies and identified wavelengths for accurate measurement of cerebral blood oxygenation. The studies demonstrated that the system may be used for noninvasive, continuous, and accurate monitoring of cerebral venous blood oxygenation.
Original language | English (US) |
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Article number | 717706 |
Journal | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Volume | 7177 |
DOIs | |
State | Published - 2009 |
Event | Photons Plus Ultrasound: Imaging and Sensing 2009 - San Jose, CA, United States Duration: Jan 25 2009 → Jan 28 2009 |
Keywords
- Cerebral blood saturation
- Clinical applications
- Noninvasive monitoring
- Optoacoustics
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
- Biomaterials