Abstract
Dopamine release and metabolism in the corpus striatum increased markedly when the core body temperature of anesthetized rats was increased from 35 ° to 41 °C while temperatures below 34 ° were associated with a marked attenuation of dopamine release. These observations may have clinical relevance in cases where alterations in body temperature are associated with extrapyramidal dysfunction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 193-196 |
| Number of pages | 4 |
| Journal | Journal of Neural Transmission |
| Volume | 89 |
| Issue number | 3 |
| DOIs | |
| State | Published - Oct 1992 |
| Externally published | Yes |
Keywords
- Dopamine
- Parkinson's disease
- body temperature
- cerebral microdialysis
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Psychiatry and Mental health
- Biological Psychiatry