Case Report: Disparate flow in HeartMate II patient with extensive left ventricle repair

Phat L. Tran, Toshinobu Kazui, Viktor Perovic, Philmon Mikail, Scott Lick, Richard Smith, Edward W. Betterton, Raj Venkat, Jessika Iwanski, Raymond K. Wong, Marvin J. Slepian, Zain Khalpey

Research output: Contribution to journalArticlepeer-review


This case study reports the operative management of a 63-year-old male patient following implantation of the HeartMate II (HMII) left ventricular assist device (LVAD), with a non-compliant left ventricle (LV) and a reduced right ventricular (RV) end-diastolic volume. Intraoperatively, the patient had a thin, fragile LV wall with laminated clot; a ventricular septal defect was encountered during removal of the clot. Along with an aortic valve repair, the LV and the septum were reconstructed with multiple bovine pericardium patches, thus, moderately reducing the RV and LV stroke volume. A difference in cardiac output via a Swan-Ganz catheter (approximately 1.5 l/min) was observed as opposed to the HMII's estimated flow. The result was later replicated and verified in vitro via the Donovan Mock Circulation System (DMCS), where about 2 l/min lower flow on the HMII system was observed. In conclusion, the HMII flow rate displayed can be inaccurate and should only be used for trending.

Original languageEnglish (US)
Pages (from-to)349-352
Number of pages4
JournalPerfusion (United Kingdom)
Issue number4
StatePublished - May 2016
Externally publishedYes


  • Donovan mock circulation system (DMCS)
  • HeartMate II (HMII)
  • left ventricular assist device (LVAD)
  • mechanical circulatory support (MCS)
  • ventricle repair/reconstruction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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