Blood Lead, Calcium Status, and Behavior in Preschool Children

Danielle Laraque, Marie Mccormick, Michael Norman, Arlene Taylor, Susan C. Weller, Joel Karp

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


To determine if calcium status is associated with blood lead levels and behavior, 64 black urban children aged 18 to 47 months were studied. Twenty-seven controls (blood lead levels, <1.45 μmol/L) were compared with 37 cases (blood lead levels, ≥1.45 μmol/L) with respect to four calcium measures (calcium intake, serum calcium level, 1,25-dihydroxyvitamin D level, and bone densitometric findings) and three behavioral scores. Levels of 25-hydroxyvitamin D provided a measure of vitamin D sufficiency. As expected, blood lead level was associated with pica scores. However, none of the calcium measures differed between cases and controls. Controlling for four confounders (season, pica score, maternal education, and sex), yielded no significant differences between the two groups in the mean values of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D level. There was no interaction between blood lead level and the four covariates. No relationship could be demonstrated between calcium status and the pica scores.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalAmerican Journal of Diseases of Children
Issue number2
StatePublished - Feb 1990

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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