Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes

Mark A. Norris; Marc S. Cohen; Michael M. Warren; Steven N. Becker; Paul S. Baur; Herbert M. Seybold

doi:10.1016/0090-4295(82)90017-6

Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes

Mark A. Norris, Marc S. Cohen, Michael M. Warren, Steven N. Becker, Paul S. Baur, Herbert M. Seybold

Surgery

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.

Original language	English (US)
Pages (from-to)	631-635
Number of pages	5
Journal	Urology
Volume	19
Issue number	6
DOIs	https://doi.org/10.1016/0090-4295(82)90017-6
State	Published - Jun 1982

ASJC Scopus subject areas

Urology

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10.1016/0090-4295(82)90017-6

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title = "Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes",

abstract = "Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.",

author = "Norris, {Mark A.} and Cohen, {Marc S.} and Warren, {Michael M.} and Becker, {Steven N.} and Baur, {Paul S.} and Seybold, {Herbert M.}",

note = "Funding Information: *This work was supported in part by a grant from Mr. Harry K. Smith, Houston, Texas. Dr. Cohen is supported by the American Urologic Association Scholars Grant.",

year = "1982",

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doi = "10.1016/0090-4295(82)90017-6",

language = "English (US)",

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pages = "631--635",

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T1 - Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes

AU - Norris, Mark A.

AU - Cohen, Marc S.

AU - Warren, Michael M.

AU - Becker, Steven N.

AU - Baur, Paul S.

AU - Seybold, Herbert M.

N1 - Funding Information: *This work was supported in part by a grant from Mr. Harry K. Smith, Houston, Texas. Dr. Cohen is supported by the American Urologic Association Scholars Grant.

PY - 1982/6

Y1 - 1982/6

N2 - Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.

AB - Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.

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Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes

Abstract

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