Biomarkers in asthma

Anandhi Murugan; Curig Prys-Picard; William J. Calhoun

doi:10.1097/MCP.0b013e32831de235

Biomarkers in asthma

Anandhi Murugan, Curig Prys-Picard, William J. Calhoun

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

To date, the best validated, and best performing biomarkers for clinical asthma appear to be measures of inflammation in induced sputum, and measures of ENO. Some trials using ENO appear particularly promising for early clinical use. EBC metrics are at present too inchoate for clinical purposes. However, not all important clinical and research questions can be addressed with sputum, EBC, or ENO metrics, leaving an important place for BAL, bronchial biopsy, and perhaps EBC measurements in the research arena.

Original language	English (US)
Pages (from-to)	12-18
Number of pages	7
Journal	Current Opinion in Pulmonary Medicine
Volume	15
Issue number	1
DOIs	https://doi.org/10.1097/MCP.0b013e32831de235
State	Published - Jan 2009

Keywords

Asthma
Biomarker
Phenotype
Prediction

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1097/MCP.0b013e32831de235

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AB - To date, the best validated, and best performing biomarkers for clinical asthma appear to be measures of inflammation in induced sputum, and measures of ENO. Some trials using ENO appear particularly promising for early clinical use. EBC metrics are at present too inchoate for clinical purposes. However, not all important clinical and research questions can be addressed with sputum, EBC, or ENO metrics, leaving an important place for BAL, bronchial biopsy, and perhaps EBC measurements in the research arena.

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KW - Phenotype

KW - Prediction

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Biomarkers in asthma

Abstract

Keywords

ASJC Scopus subject areas

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