TY - JOUR
T1 - Better Safe than Sorry
T2 - A Dual-Function Viral Protein Inhibiting Host Defense
AU - Lechtenberg, Bernhard C.
AU - Routh, Andrew
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/10/10
Y1 - 2018/10/10
N2 - Viruses employ intricate means to evade host innate immune systems. In this issue of Cell Host & Microbe, Nayak et al. (2018) demonstrate that the cricket paralysis virus (CrPV) protein CrPV-1A blocks host defense through a dual mechanism: directly inhibiting Argonaute2 (Ago2) and simultaneously targeting Ago2 for proteasomal degradation. Viruses employ intricate means to evade host innate immune systems. In this issue of Cell Host & Microbe, Nayak et al. (2018) demonstrate that the cricket paralysis virus (CrPV) protein CrPV-1A blocks host defense through a dual mechanism: directly inhibiting Argonaute2 (Ago2) and simultaneously targeting Ago2 for proteasomal degradation.
AB - Viruses employ intricate means to evade host innate immune systems. In this issue of Cell Host & Microbe, Nayak et al. (2018) demonstrate that the cricket paralysis virus (CrPV) protein CrPV-1A blocks host defense through a dual mechanism: directly inhibiting Argonaute2 (Ago2) and simultaneously targeting Ago2 for proteasomal degradation. Viruses employ intricate means to evade host innate immune systems. In this issue of Cell Host & Microbe, Nayak et al. (2018) demonstrate that the cricket paralysis virus (CrPV) protein CrPV-1A blocks host defense through a dual mechanism: directly inhibiting Argonaute2 (Ago2) and simultaneously targeting Ago2 for proteasomal degradation.
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U2 - 10.1016/j.chom.2018.09.012
DO - 10.1016/j.chom.2018.09.012
M3 - Short survey
C2 - 30308151
AN - SCOPUS:85054003648
SN - 1931-3128
VL - 24
SP - 467
EP - 469
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 4
ER -