Behavior of Leishmania braziliensis s.l. in golden hamsters: Evolution of the infection under different experimental conditions

B. Travi; J. Rey-Ladino; N. G. Saravia

doi:10.2307/3282237

Behavior of Leishmania braziliensis s.l. in golden hamsters: Evolution of the infection under different experimental conditions

B. Travi, J. Rey-Ladino, N. G. Saravia

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20 Scopus citations

Abstract

Reproducibility of Leishmania braziliensis s.l. metastatic behavior in hamsters was studied for 9 isolates of L. b. panamensis and 2 of L. b. guyanensis with a previous record of metastasis. Also, the influence of corticosteroids and trauma was evaluated. In the corticosteroid-treated group, metastases appeared earlier than in the nontreated group, and localization at the site of trauma was more frequent (4/9) than in the nontreated hamsters (1/5). Nine of the 11 strains (82%) were capable of reproducing metastatic behavior. Studies on dissemination of L. b. panamensis showed that the regional lymph node is invaded as soon as 5 days postinfection, with further nonhematic dissemination to other tissues and organs in less than 4 wk.

Original language	English (US)
Pages (from-to)	1059-1062
Number of pages	4
Journal	Journal of Parasitology
Volume	74
Issue number	6
DOIs	https://doi.org/10.2307/3282237
State	Published - 1988
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Ecology, Evolution, Behavior and Systematics

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title = "Behavior of Leishmania braziliensis s.l. in golden hamsters: Evolution of the infection under different experimental conditions",

abstract = "Reproducibility of Leishmania braziliensis s.l. metastatic behavior in hamsters was studied for 9 isolates of L. b. panamensis and 2 of L. b. guyanensis with a previous record of metastasis. Also, the influence of corticosteroids and trauma was evaluated. In the corticosteroid-treated group, metastases appeared earlier than in the nontreated group, and localization at the site of trauma was more frequent (4/9) than in the nontreated hamsters (1/5). Nine of the 11 strains (82%) were capable of reproducing metastatic behavior. Studies on dissemination of L. b. panamensis showed that the regional lymph node is invaded as soon as 5 days postinfection, with further nonhematic dissemination to other tissues and organs in less than 4 wk.",

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AU - Saravia, N. G.

PY - 1988

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AB - Reproducibility of Leishmania braziliensis s.l. metastatic behavior in hamsters was studied for 9 isolates of L. b. panamensis and 2 of L. b. guyanensis with a previous record of metastasis. Also, the influence of corticosteroids and trauma was evaluated. In the corticosteroid-treated group, metastases appeared earlier than in the nontreated group, and localization at the site of trauma was more frequent (4/9) than in the nontreated hamsters (1/5). Nine of the 11 strains (82%) were capable of reproducing metastatic behavior. Studies on dissemination of L. b. panamensis showed that the regional lymph node is invaded as soon as 5 days postinfection, with further nonhematic dissemination to other tissues and organs in less than 4 wk.

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Behavior of Leishmania braziliensis s.l. in golden hamsters: Evolution of the infection under different experimental conditions

Abstract

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