B to A transition of DNA on the nanosecond time scale

Liqiu Yang; B. Montgomery Pettitt

doi:10.1021/jp953080f

B to A transition of DNA on the nanosecond time scale

Liqiu Yang, B. Montgomery Pettitt

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

Abstract

A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor III.

Original language	English (US)
Pages (from-to)	2564-2566
Number of pages	3
Journal	Journal of physical chemistry
Volume	100
Issue number	7
DOIs	https://doi.org/10.1021/jp953080f
State	Published - Feb 15 1996
Externally published	Yes

ASJC Scopus subject areas

General Engineering
Physical and Theoretical Chemistry

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10.1021/jp953080f

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title = "B to A transition of DNA on the nanosecond time scale",

abstract = "A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor III.",

author = "Liqiu Yang and Pettitt, {B. Montgomery}",

year = "1996",

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day = "15",

doi = "10.1021/jp953080f",

language = "English (US)",

volume = "100",

pages = "2564--2566",

journal = "Journal of physical chemistry",

issn = "0022-3654",

publisher = "American Chemical Society",

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T1 - B to A transition of DNA on the nanosecond time scale

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AU - Pettitt, B. Montgomery

PY - 1996/2/15

Y1 - 1996/2/15

N2 - A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor III.

AB - A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor III.

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U2 - 10.1021/jp953080f

DO - 10.1021/jp953080f

M3 - Article

AN - SCOPUS:33748674257

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SP - 2564

EP - 2566

JO - Journal of physical chemistry

JF - Journal of physical chemistry

IS - 7

ER -

B to A transition of DNA on the nanosecond time scale

Abstract

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