Attack behaviour in mice inhibited by Δ-9-Tetrahydrocannabinol

M. Marlyne Kilbey; G. Edward Fritchie; David M. Mclendon; Kenneth M. Johnson

doi:10.1038/238463a0

Attack behaviour in mice inhibited by Δ-9-Tetrahydrocannabinol

M. Marlyne Kilbey, G. Edward Fritchie, David M. Mclendon, Kenneth M. Johnson

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice¹ and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack². The degree of suppression of fighting behaviour seemed to be related to the cannabis resin content of the extract administered ¹. The behavioural effects which we reported² could not be assessed for a THC dose-dependent relationship as some mice in the low-dosage group received faulty intravenous injections.

Original language	English (US)
Pages (from-to)	463-465
Number of pages	3
Journal	Nature
Volume	238
Issue number	5365
DOIs	https://doi.org/10.1038/238463a0
State	Published - 1972
Externally published	Yes

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title = "Attack behaviour in mice inhibited by Δ-9-Tetrahydrocannabinol",

abstract = "MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice1 and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack2. The degree of suppression of fighting behaviour seemed to be related to the cannabis resin content of the extract administered 1. The behavioural effects which we reported2 could not be assessed for a THC dose-dependent relationship as some mice in the low-dosage group received faulty intravenous injections.",

author = "Kilbey, {M. Marlyne} and Fritchie, {G. Edward} and Mclendon, {David M.} and Johnson, {Kenneth M.}",

year = "1972",

doi = "10.1038/238463a0",

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AU - Kilbey, M. Marlyne

AU - Fritchie, G. Edward

AU - Mclendon, David M.

AU - Johnson, Kenneth M.

PY - 1972

Y1 - 1972

N2 - MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice1 and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack2. The degree of suppression of fighting behaviour seemed to be related to the cannabis resin content of the extract administered 1. The behavioural effects which we reported2 could not be assessed for a THC dose-dependent relationship as some mice in the low-dosage group received faulty intravenous injections.

AB - MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice1 and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack2. The degree of suppression of fighting behaviour seemed to be related to the cannabis resin content of the extract administered 1. The behavioural effects which we reported2 could not be assessed for a THC dose-dependent relationship as some mice in the low-dosage group received faulty intravenous injections.

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JO - Nature

JF - Nature

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ER -

Attack behaviour in mice inhibited by Δ-9-Tetrahydrocannabinol

Abstract

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