Assessing antiviral countermeasures using mouse models of ebolavirus infection

Andrea Kroeker, Bryan D. Griffin, Xiangguo Qiu, Gary Kobinger

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Mouse models of Ebola virus (EBOV) have demonstrated their utility as important tools for screening the efficacy of candidate therapeutics and vaccines. In this chapter we explain the various mouse models that utilize either wild-type or mouse-adapted EBOV variants.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages273-282
Number of pages10
DOIs
StatePublished - 2017
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1628
ISSN (Print)1064-3745

Keywords

  • Animal model
  • Antiviral
  • Drug therapy
  • Ebola virus
  • Monoclonal antibodies
  • Mouse
  • Recombinant vesicular stomatitis virus (rVSV)
  • Vaccine

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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