Abstract
Although the shapes of organisms are encoded in their genome, the developmental processes that lead to the final form of vertebrates involve a constant feedback between dynamic mechanical forces, and cell growth and motility. Mechanobiology has emerged as a discipline dedicated to the study of the effects of mechanical forces and geometry on cell growth and motility-for example, during cell-matrix adhesion development-through the signalling process of mechanotransduction.
Original language | English (US) |
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Pages (from-to) | 825-833 |
Number of pages | 9 |
Journal | Nature Reviews Molecular Cell Biology |
Volume | 15 |
Issue number | 12 |
DOIs | |
State | Published - Dec 11 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology