TY - JOUR
T1 - Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
AU - de Souza, William Marciel
AU - Machado, Alex Martins
AU - Disner, Geonildo Rodrigo
AU - Boff, Everton
AU - Machado, Aline Rafaela da Silva Rodrigues
AU - de Padua, Michelly
AU - Figueiredo, Luiz Tadeu Moraes
AU - de Miranda, Gustavo Borba
PY - 2012/7
Y1 - 2012/7
N2 - Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.
AB - Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.
KW - Argentina
KW - Brazil
KW - Epidemiology
KW - Hantavirus
KW - Santa Catarina
UR - http://www.scopus.com/inward/record.url?scp=84864973985&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864973985&partnerID=8YFLogxK
U2 - 10.1590/S0036-46652012000400002
DO - 10.1590/S0036-46652012000400002
M3 - Article
C2 - 22850989
AN - SCOPUS:84864973985
SN - 0036-4665
VL - 54
SP - 193
EP - 196
JO - Revista do Instituto de Medicina Tropical de Sao Paulo
JF - Revista do Instituto de Medicina Tropical de Sao Paulo
IS - 4
ER -