TY - JOUR
T1 - Antenatal factors associated with significant birth weight discordancy in twin gestations
AU - González-Quintero, Víctor H.
AU - Luke, Barbara
AU - O'Sullivan, Mary J.
AU - Misiunas, Ruta
AU - Anderson, Elaine
AU - Nugent, Clark
AU - Witter, Frank
AU - Mauldin, Jill
AU - Newman, Roger
AU - D'Alton, Mary
AU - Grainger, David
AU - Saade, George
AU - Hankins, Gary
AU - Macones, George
PY - 2003/9/1
Y1 - 2003/9/1
N2 - OBJECTIVE: The purpose of this study was to evaluate factors that are associated with significant birth weight discordancy. STUDY DESIGN: As a part of an ongoing collaborative study of twins, maternal and fetal data were obtained from the medical records of twin gestations at eight medical centers. The study population was divided into groups by difference in birth weight discordancy (≥20%, ≥25%, and ≥30%) RESULTS: Severe birth weight discordancy was associated with fetal growth deceleration by 20 to 28 weeks (adjusted odds ratio, 4.90; 95% CI, 3.15-7.64) and between 28 weeks to birth (adjusted odds ratio, 3.48; 95% CI, 1.72-7.06). Antenatal bleeding (adjusted odds ratio, 1.86; 95% CI, 1.08-3.21), preeclampsia (adjusted odds ratio, 1.70, 95% CI, 1.21-2.41), and monochorionicity (adjusted odds ratio, 2.35, 95% CI, 11.71-3.23) were also associated with birth weight discordancy. CONCLUSION: These data demonstrate the importance of the early diagnosis of placental chorionicity, because monochorionicity is associated with a 2-fold increase in birth weight discordancy in twin gestations.
AB - OBJECTIVE: The purpose of this study was to evaluate factors that are associated with significant birth weight discordancy. STUDY DESIGN: As a part of an ongoing collaborative study of twins, maternal and fetal data were obtained from the medical records of twin gestations at eight medical centers. The study population was divided into groups by difference in birth weight discordancy (≥20%, ≥25%, and ≥30%) RESULTS: Severe birth weight discordancy was associated with fetal growth deceleration by 20 to 28 weeks (adjusted odds ratio, 4.90; 95% CI, 3.15-7.64) and between 28 weeks to birth (adjusted odds ratio, 3.48; 95% CI, 1.72-7.06). Antenatal bleeding (adjusted odds ratio, 1.86; 95% CI, 1.08-3.21), preeclampsia (adjusted odds ratio, 1.70, 95% CI, 1.21-2.41), and monochorionicity (adjusted odds ratio, 2.35, 95% CI, 11.71-3.23) were also associated with birth weight discordancy. CONCLUSION: These data demonstrate the importance of the early diagnosis of placental chorionicity, because monochorionicity is associated with a 2-fold increase in birth weight discordancy in twin gestations.
KW - Birth weight discordancy
KW - Monochorionicity
KW - Twin gestation
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U2 - 10.1067/S0002-9378(03)00658-6
DO - 10.1067/S0002-9378(03)00658-6
M3 - Article
C2 - 14526320
AN - SCOPUS:0141748170
SN - 0002-9378
VL - 189
SP - 813
EP - 817
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 3
ER -