TY - JOUR
T1 - Acute normovolemic red cell exchange for cardiopulmonary bypass in sickle cell disease
AU - Shulman, Gerald
AU - McQuitty, Christopher
AU - Vertrees, Roger A.
AU - Conti, Vincent R.
N1 - Funding Information:
We acknowledge Medtronic Electromedics Inc, Parker, Colorado, for financial support in performing the investigations of the study.
PY - 1998/5
Y1 - 1998/5
N2 - A patient with sickle cell disease (hematocrit, 28.5%; hemoglobin S fraction, 79%), required mitral valve repair. Partial red cell removal and blood component sequestration with an autotransfusion device before cardiopulmonary bypass initially decreased the sickle red cell mass. This was followed by an acute one-volume whole blood exchange transfusion performed upon the initiation of cardiopulmonary bypass, resulting in a further reduction. Both techniques yielded fresh autologous plasma for use; sequestration yielded a platelet-pheresis product. Adequate postbypass hemostasis was demonstrated.
AB - A patient with sickle cell disease (hematocrit, 28.5%; hemoglobin S fraction, 79%), required mitral valve repair. Partial red cell removal and blood component sequestration with an autotransfusion device before cardiopulmonary bypass initially decreased the sickle red cell mass. This was followed by an acute one-volume whole blood exchange transfusion performed upon the initiation of cardiopulmonary bypass, resulting in a further reduction. Both techniques yielded fresh autologous plasma for use; sequestration yielded a platelet-pheresis product. Adequate postbypass hemostasis was demonstrated.
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U2 - 10.1016/S0003-4975(98)00038-1
DO - 10.1016/S0003-4975(98)00038-1
M3 - Article
C2 - 9594885
AN - SCOPUS:0032076077
SN - 0003-4975
VL - 65
SP - 1444
EP - 1446
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 5
ER -