A survey for antibodies to Lassa virus among health workers in Nigeria

M. D. Bajani; O. Tomori; P. E. Rollin; T. O. Harry; N. D. Bukbuk; L. Wilson; J. E. Childs; C. J. Peters; T. G. Ksiazek

doi:10.1016/S0035-9203(97)90247-9

A survey for antibodies to Lassa virus among health workers in Nigeria

M. D. Bajani, O. Tomori, P. E. Rollin, T. O. Harry, N. D. Bukbuk, L. Wilson, J. E. Childs, C. J. Peters, T. G. Ksiazek

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12.3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1.2% to 27.3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1.7% to 23.7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.

Original language	English (US)
Pages (from-to)	379-381
Number of pages	3
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	91
Issue number	4
DOIs	https://doi.org/10.1016/S0035-9203(97)90247-9
State	Published - 1997
Externally published	Yes

Keywords

Health workers
Lassa fever
Nigeria
Seroprevalence

ASJC Scopus subject areas

Parasitology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/S0035-9203(97)90247-9

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title = "A survey for antibodies to Lassa virus among health workers in Nigeria",

abstract = "A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12.3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1.2% to 27.3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1.7% to 23.7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.",

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AU - Bajani, M. D.

AU - Tomori, O.

AU - Rollin, P. E.

AU - Harry, T. O.

AU - Bukbuk, N. D.

AU - Wilson, L.

AU - Childs, J. E.

AU - Peters, C. J.

AU - Ksiazek, T. G.

PY - 1997

Y1 - 1997

N2 - A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12.3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1.2% to 27.3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1.7% to 23.7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.

AB - A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12.3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1.2% to 27.3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1.7% to 23.7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.

KW - Health workers

KW - Lassa fever

KW - Nigeria

KW - Seroprevalence

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A survey for antibodies to Lassa virus among health workers in Nigeria

Abstract

Keywords

ASJC Scopus subject areas

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