A self-cleaving DNA nucleoside

Vineet Gupta, Eric T. Kool

Research output: Contribution to journalArticlepeer-review

Abstract

An allyl-modified nucleoside has been shown to self-alkylate and depurinate on treatment with iodine and heat; placement in DNA strands yields site-directed cleavage of the DNA.

Original languageEnglish (US)
Pages (from-to)1425-1426
Number of pages2
JournalChemical Communications
Issue number15
DOIs
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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