TY - JOUR
T1 - A change in α-crystallin subunit composition in relation to cellular differentiation in adult bovine lens
AU - Delcour, Jean
AU - Papaconstantinou, John
PY - 1970/10/23
Y1 - 1970/10/23
N2 - The vertebrate lens is composed of two distinct cell types, the epithelial cell and the fiber cell. α-Crystallin, a structural protein found in both cell types, is composed of four subunits (αA1, αA2, αB1, and αB2). In the epithelial cells the α-crystallin consists mainly of αA2 and αB2 with trace amounts of αA1 and αB1. In the fiber cell there is a large increase in the amount of αA1 and αB1 subunits. This quantitative increase in two specific subunits is related to the process of cellular growth and differentiation in the vertebrate lens.
AB - The vertebrate lens is composed of two distinct cell types, the epithelial cell and the fiber cell. α-Crystallin, a structural protein found in both cell types, is composed of four subunits (αA1, αA2, αB1, and αB2). In the epithelial cells the α-crystallin consists mainly of αA2 and αB2 with trace amounts of αA1 and αB1. In the fiber cell there is a large increase in the amount of αA1 and αB1 subunits. This quantitative increase in two specific subunits is related to the process of cellular growth and differentiation in the vertebrate lens.
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U2 - 10.1016/0006-291X(70)90518-8
DO - 10.1016/0006-291X(70)90518-8
M3 - Article
C2 - 5518168
AN - SCOPUS:0014959915
SN - 0006-291X
VL - 41
SP - 401
EP - 406
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -