A case of Guillain-Barre syndrome with immunologic abnormalities

C. J. Froelich, R. P. Searles, L. E. Davis, J. S. Goodwin

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Guillain-Barre syndrome and the nephrotic syndrome developed in a patient simultaneously. Analysis of renal biopsy by light, immunofluorescent, and electron microscopy showed lipoid nephrosis. T-cell lymphocytopenia, lymphocytotoxic antibodies, depressed lymphocyte mitogenesis, and anergy also complicated the illness. The immunologic abnormalities resolved when the polyradiculoneuritis and lipoid nephrosis remitted. This previously undescribed association illustrates the occurrence of two postulated cell-mediated autoimmune disorders despite the presence of depressed cell-mediated immunity.

Original languageEnglish (US)
Pages (from-to)563-565
Number of pages3
JournalAnnals of internal medicine
Issue number4
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine


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