Interplay of Physiological, Psychosocial, and Functional Outcomes in Burn Survivors

The University of Texas Medical Branch, the Henry M. Jackson Foundation for the Advancement of Military Medicine and the U.S. Army Institute of Surgical Research will partner in this three-year project. This project will increase the integrative, comprehensive knowledge, and usefulness of the physical function (PF) outcome information that is like that contained in the National Institute on Disability, Independent Living and Rehabilitation Research Burn Model System National Database. The overall research question of this project is: what are the levels or strength of associations of a well-established subjective test of physical function (i.e., PROMIS 29) and two well-established objective tests of physical function (i.e., standardized treadmill test, and dynamometry)? The overall goal of this project is to measure physical function (PF) as a health outcome in survivors of a severe burn. The specific objective of the project is to conduct these measurements using both physiological and psychosocial tests. In this manner, the level of association between self-perceived and physiological PF information will be obtained. By doing this, we will have integrative, robust data that can be used to better guide potential therapies or interventions to improve PF in the future. Primary outcomes are: 1) Self-perceived PF scores in the Patient Reported Outcomes Information System (PROMIS 29) survey, 2) cardiopulmonary treadmill exercise performance, 3) large muscle performance. Secondary outcomes are other domains of the PROMIS 29, such as anxiety, fatigue, sleep disturbance, and depression. The expected product is key information on PF mental health and physical health that can benefit survivors of severe burns, and more accurately guide rehabilitation therapies. PREVIEW Date: Dec 16, 2022Workspace ID: WS00990496 Funding Opportunity Number: HHS-2023-ACL-NIDILRR-IFRE-0000