Ananth Kumar Kammala

2024

High-Throughput 3D-Printed Model of the Feto-Maternal Interface for the Discovery and Development of Preterm Birth Therapies

Cherukuri, R., Kammala, A. K., Thomas, T. J., Saylor, L., Richardson, L., Kim, S., Ferrer, M., Acedo, C., Song, M. J., Gaharwar, A. K., Menon, R. & Han, A., Aug 14 2024, In: ACS Applied Materials and Interfaces. 16, 32, p. 41892-41906 15 p.

Research output: Contribution to journal › Article › peer-review

Are fetal microchimerism and circulating fetal extracellular vesicles important links between spontaneous preterm delivery and maternal cardiovascular disease risk?

Bonney, E. A., Lintao, R. C. V., Zelop, C. M., Kammala, A. K. & Menon, R., Apr 2024, In: BioEssays. 46, 4, 2300170.

Research output: Contribution to journal › Article › peer-review

Pharmacological properties of mangiferin: bioavailability, mechanisms of action and clinical perspectives

Zivković, J., Kumar, K. A., Rushendran, R., Ilango, K., Fahmy, N. M., El-Nashar, H. A. S., El-Shazly, M., Ezzat, S. M., Melgar-Lalanne, G., Romero-Montero, A., Peña-Corona, S. I., Leyva-Gomez, G., Sharifi-Rad, J. & Calina, D., Feb 2024, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 397, 2, p. 763-781 19 p.

Research output: Contribution to journal › Review article › peer-review

New approach methods on the bench side to accelerate clinical trials during pregnancy

Menon, R., Richardson, L. & Kammala, A. K., 2024, In: Expert Opinion on Drug Metabolism and Toxicology. 20, 7, p. 555-560 6 p.

Research output: Contribution to journal › Article › peer-review

2023

Development of oxidative stress-associated disease models using feto-maternal interface organ-on-a-chip

Richardson, L. S., Kammala, A. K., Kim, S., Lam, P. Y., Truong, N., Radnaa, E., Urrabaz-Garza, R., Han, A. & Menon, R., Jul 1 2023, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37, 7, p. e23000

Research output: Contribution to journal › Article › peer-review

Open Access

Fetal membranes exhibit similar nutrient transporter expression profiles to the placenta

Lintao, R. C. V., Kammala, A. K., Vora, N., Yaklic, J. L. & Menon, R., Apr 2023, In: Placenta. 135, p. 33-42 10 p.

Research output: Contribution to journal › Article › peer-review

2022

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

Sreenivasmurthy, S. G., Iyaswamy, A., Krishnamoorthi, S., Reddi, R. N., Kammala, A. K., Vasudevan, K., Senapati, S., Zhu, Z., Su, C. F., Liu, J., Guan, X. J., Chua, K. K., Cheung, K. H., Chen, H., Zhang, H. J., Zhang, Y., Song, J. X., Kumar Durairajan, S. S. & Li, M., Oct 26 2022, In: Frontiers in Molecular Biosciences. 9, 1030534.

Research output: Contribution to journal › Article › peer-review

Open Access

Expression of CYP450 enzymes in human fetal membranes and its implications in xenobiotic metabolism during pregnancy

Kammala, A. K., Lintao, R. C. V., Vora, N., Mosebarger, A., Khanipov, K., Golovko, G., Yaklic, J. L., Peltier, M. R., Conrads, T. P. & Menon, R., Oct 15 2022, In: Life Sciences. 307, 120867.

Research output: Contribution to journal › Article › peer-review

Open Access

Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina-cervix-decidua-organ-on-a-chip and feto-maternal interface-organ-on-a-chip

Tantengco, O. A. G., Richardson, L. S., Radnaa, E., Kammala, A. K., Kim, S., Medina, P. M. B., Han, A. & Menon, R., Oct 2022, In: FASEB Journal. 36, 10, e22551.

Research output: Contribution to journal › Article › peer-review

Open Access

Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery

Tantengco, O. A. G., Richardson, L. S., Radnaa, E., Kammala, A. K., Kim, S., Medina, P. M. B., Han, A. & Menon, R., Aug 15 2022, In: Frontiers in Cell and Developmental Biology. 10, 931609.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of Plasma Level of Heme-Oxygenase-1 in Neonatal Hypoxic Ischemic Encephalopathy

Mafinezhad, S., Bayani, G., Ehteshammanesh, H., Kammala, A. K. & Ahmadabad, H. N., Jul 1 2022, In: Journal of Kerman University of Medical Sciences. 29, 4, p. 378-384 7 p.

Research output: Contribution to journal › Article › peer-review

Computational Screening of the Natural Product Osthole and Its Derivates for Anti-Inflammatory Activity

Mosebarger, A., Reddi, R. N., Menon, R. & Kammala, A. K., Apr 2022, In: Life. 12, 4, 505.

Research output: Contribution to journal › Article › peer-review

Open Access

Computer Aided Drug Design Approach to Screen Phytoconstituents of Adhatoda vasica as Potential Inhibitors of SARS-CoV-2 Main Protease Enzyme

Kumar, B. S., Anuragh, S., Kammala, A. K. & Ilango, K., Feb 2022, In: Life. 12, 2, 315.

Research output: Contribution to journal › Article › peer-review

Open Access

Fetal Membranes Contribute to Drug Transport across the Feto-Maternal Interface Utilizing the Breast Cancer Resistance Protein (BCRP)

Kammala, A., Benson, M., Ganguly, E., Radnaa, E., Kechichian, T., Richardson, L. & Menon, R., Feb 2022, In: Life. 12, 2, 166.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional role and regulation of permeability-glycoprotein (P-gp) in the fetal membrane during drug transportation

Kammala, A., Benson, M., Ganguly, E., Richardson, L. & Menon, R., Feb 2022, In: American Journal of Reproductive Immunology. 87, 2, e13515.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Organic Anion Transporting Polypeptide 2B1 in Human Fetal Membranes: A Novel Gatekeeper for Drug Transport During Pregnancy?

Ganguly, E., Kammala, A. K., Benson, M., Richardson, L. S., Han, A. & Menon, R., Dec 20 2021, In: Frontiers in Pharmacology. 12, 771818.

Research output: Contribution to journal › Article › peer-review

Open Access

Development of a mouse model of ascending infection and preterm birth

Spencer, N. R., Radnaa, E., Baljinnyam, T., Kechichian, T., Tantengco, O. A. G., Bonney, E., Kammala, A. K., Sheller-Miller, S. & Menon, R., Dec 2021, In: PloS one. 16, 12 December, e0260370.

Research output: Contribution to journal › Article › peer-review

Open Access

Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response

Shepherd, M. C., Radnaa, E., Tantengco, O. A., Kechichian, T., Urrabaz-Garza, R., Kammala, A. K., Sheller-Miller, S. & Menon, R., Dec 2021, In: Cell Communication and Signaling. 19, 1, 100.

Research output: Contribution to journal › Article › peer-review

Open Access

Ruxolitinib Ameliorates Airway Hyperresponsiveness and Lung Inflammation in a Corticosteroid-Resistant Murine Model of Severe Asthma

Subramanian, H., Hashem, T., Bahal, D., Kammala, A. K., Thaxton, K. & Das, R., Oct 29 2021, In: Frontiers in immunology. 12, 786238.

Research output: Contribution to journal › Article › peer-review

Open Access

Histocompatibility antigen, class i, g (Hla-g)’s role during pregnancy and parturition: A systematic review of the literature

Tantengco, O. A. G., Richardson, L., Lee, A., Kammala, A., Silva, M. D. C., Shahin, H., Sheller-Miller, S. & Menon, R., Oct 2021, In: Life. 11, 10, 1061.

Research output: Contribution to journal › Review article › peer-review

Open Access

Lactic acid suppresses MRGPRX2 mediated mast cell responses

Syed, M., Kammala, A. K., Callahan, B., Oskeritzian, C. A. & Subramanian, H., Oct 2021, In: Cellular Immunology. 368, 104422.

Research output: Contribution to journal › Article › peer-review

Open Access

Microvesicles and exosomes released by amnion epithelial cells under oxidative stress cause inflammatory changes in uterine cells^†

Shahin, H. I., Radnaa, E., Tantengco, O. A. G., Kechichian, T., Kammala, A. K., Sheller-Miller, S., Taylor, B. D. & Menon, R., Aug 2021, In: Biology of reproduction. 105, 2, p. 464-480 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Extracellular vesicle mediated feto-maternal HMGB1 signaling induces preterm birth

Radnaa, E., Richardson, L. S., Sheller-Miller, S., Baljinnyam, T., De Castro Silva, M., Kumar Kammala, A., Urrabaz-Garza, R., Kechichian, T., Kim, S., Han, A. & Menon, R., May 21 2021, In: Lab on a Chip. 21, 10, p. 1956-1973 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Na⁺/H⁺ exchanger regulatory factor 1 mediates the pathogenesis of airway inflammation in a murine model of house dust miteinduced asthma

Kammala, A. K., Bahal, D., Yang, C., Panettieri, R. A., Das, R. & Subramanian, H., May 15 2021, In: Journal of Immunology. 206, 10, p. 2301-2311 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A critical role for Na⁺/H⁺ exchanger regulatory factor 1 in modulating Fc«RI-mediated mast cell activation

Kammala, A. K., Syed, M., Yang, C., Occhiuto, C. J. & Subramanian, H., Feb 1 2021, In: Journal of Immunology. 206, 3, p. 471-480 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

G Protein-Coupled Receptor Kinase 2 (GRK2) Regulates T Cell Response in a Murine Model of House Dust Mite-Induced Asthma

Kammala, A. K., Yang, C., Panettieri, R. A., Das, R. & Subramanian, H., 2021, In: Frontiers in Allergy. 2, 656886.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Modified Huang-Lian-Jie-Du-Tang and its combination with memantine for Alzheimer disease: an in vivo study (abridged secondary publication)

Durairajan, S. S. K., Li, M., Chung, S. K., Han, Q. B., Iyaswamy, A., Sreenivasmurthy, S. G., Malampati, S. & Kammala, A. K., Dec 1 2020, In: Journal of the Hong Kong Medical Association. 26, 6, p. 33-36 4 p.

Research output: Contribution to journal › Article › peer-review

Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease

Iyaswamy, A., Krishnamoorthi, S. K., Liu, Y. W., Song, J. X., Kammala, A. K., Sreenivasmurthy, S. G., Malampati, S., Tong, B. C. K., Selvarasu, K., Cheung, K. H., Lu, J. H., Tan, J. Q., Huang, C. Y., Durairajan, S. S. K. & Li, M., Oct 30 2020, In: Frontiers in Pharmacology. 11, 584770.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Sodium hydrogen exchanger regulatory factor-1 (NHERF1) regulates fetal membrane inflammation

Kammala, A. K., Sheller-Miller, S., Radnaa, E., Kechichian, T., Subramanian, H. & Menon, R., Oct 2 2020, In: International journal of molecular sciences. 21, 20, p. 1-17 17 p., 7747.

Research output: Contribution to journal › Article › peer-review

Open Access

CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract

Hashem, T., Kammala, A. K., Thaxton, K., Griffin, R. M., Mullany, K., Panettieri, R. A., Subramanian, H. & Das, R., May 12 2020, In: Frontiers in immunology. 11, 881.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses

Callahan, B. N., Kammala, A. K., Syed, M., Yang, C., Occhiuto, C. J., Nellutla, R., Chumanevich, A. P., Oskeritzian, C. A., Das, R. & Subramanian, H., Apr 24 2020, In: Frontiers in immunology. 11, 703.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions

Occhiuto, C. J., Kammala, A. K., Yang, C., Nellutla, R., Garcia, M., Gomez, G. & Subramanian, H., Jan 21 2020, In: Frontiers in immunology. 10, 3143.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2018

Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model

Iyaswamy, A., Kammella, A. K., Thavasimuthu, C., Wankupar, W., Dapkupar, W., Shanmugam, S., Rajan, R. & Rathinasamy, S., Apr 2018, In: Journal of Food and Drug Analysis. 26, 2, p. 903-916 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2017

A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer's disease

Durairajan, S. S. K., Iyaswamy, A., Shetty, S. G., Kammella, A. K., Malampati, S., Shang, W., Yang, C., Song, J., Chung, S., Huang, J., Ilango, K., Han, Q. B. & Li, M., Dec 1 2017, In: Scientific reports. 7, 1, 6238.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Roles of NHERF Family of PDZ-Binding Proteins in Regulating GPCR Functions

Broadbent, D., Ahmadzai, M. M., Kammala, A. K., Yang, C., Occhiuto, C., Das, R. & Subramanian, H., 2017, Advances in Immunology. Academic Press Inc., p. 353-385 33 p. (Advances in Immunology; vol. 136).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

14 Scopus citations

2015

Antidiabetic and antihyperlipidemic activities of a novel polyherbal formulation in high fat diet/streptozotocin induced diabetic rat model

Subhasree, N., Kamella, A., Kaliappan, I., Agrawal, A. & Dubey, G. P., Sep 1 2015, In: Indian Journal of Pharmacology. 47, 5, p. 509-513 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Comparative pharmacokinetic interactions of Quercetin and Rutin in rats after oral administration of European patented formulation containing Hipphophae rhamnoides and Co-administration of Quercetin and Rutin

Kammalla, A. K., Ramasamy, M. K., Chintala, J., Dubey, G. P., Agrawal, A. & Kaliappan, I., Sep 1 2015, In: European Journal of Drug Metabolism and Pharmacokinetics. 40, 3, p. 277-284 8 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Comparative Pharmacokinetic Study of Mangiferin After Oral Administration of Pure Mangiferin and US Patented Polyherbal Formulation to Rats

Kammalla, A. K., Ramasamy, M. K., Inampudi, J., Dubey, G. P., Agrawal, A. & Kaliappan, I., Apr 1 2015, In: AAPS PharmSciTech. 16, 2, p. 250-258 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2014

Development and validation of a RP-HPLC method for the simultaneous determination of Mangiferin, Ellagic acid and Hydroxycitric acid in polyherbal formulation

Kammalla, A. K., Ramasamy, M. K., Agarwal, A., Dubey, G. P. & Ilango, K., 2014, In: Pharmacognosy Journal. 6, 3, p. 23-28 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2013

Emerging need of pharmacokinetics in Ayurvedic system of medicine

Kaliappan, I., Kammalla, A. K., Ramasamy, M. K., Agrawal, A. & Dubey, G. P., Sep 2013, In: International Journal of Research in Ayurveda and Pharmacy. 4, 5, p. 647-651 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

Estimation and validation of gallic acid in polyherbal formulation by HPTLC

Mohan Kumar, R., Ilango, K., Ananth Kumar, K., Kasthuri Bai, N., Dubey, G. P. & Agrawal, A., 2013, In: International Journal of Pharmacy and Pharmaceutical Sciences. 5, SUPPL.4, p. 203-206 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Pharmacognostic studies on the leaves of Hippophae rhamnoides L. and Hippophae salicifolia D. Don

Ilango, K., Kasthuri Bai, N., Mohan Kumar, R., Ananth Kumar, K., Dubey, G. P. & Agrawal, A., 2013, In: Research Journal of Medicinal Plant. 7, 1, p. 58-67 10 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Target identification and validation for diabetic nephropathy using molecular docking studies

Ramanjaneyulu, M., Ananth Kumar, K., Shubash Kumar, M., Reddy, S., Kara, D., Mukthala, P., Raj, R. & Madhu, C., 2013, In: Der Pharma Chemica. 5, 6, p. 353-363 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2011

Evaluation of immunomodulatory effect of hydroalcoholic root extract of Chlorophytum arundinaeceum Baker in mice

Ananth Kumar, K., Chitra, V., Leela Krishna, V. & Soujanya, J., 2011, In: International Journal of Pharmacy and Pharmaceutical Sciences. 3, SUPPL. 5, p. 355-359 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2023

Amplification of microbial DNA from bacterial extracellular vesicles from human placenta

Menon, R., Khanipov, K., Radnaa, E., Ganguly, E., Bento, G. F. C., Urrabaz-Garza, R., Kammala, A. K., Yaklic, J., Pyles, R., Golovko, G. & Tantengco, O. A. G., 2023, In: Frontiers in Microbiology. 14, 1213234.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 855.

Research output: Contribution to journal › Article › peer-review

Open Access

Cargo exchange between human and bacterial extracellular vesicles in gestational tissues: a new paradigm in communication and immune development

Amabebe, E., Kumar, A., Tatiparthy, M., Kammala, A. K., Taylor, B. D. & Menon, R., 2024, In: Extracellular Vesicles and Circulating Nucleic Acids. 5, 2, p. 297-328 32 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2023

Characterization of fetal microchimeric immune cells in mouse maternal hearts during physiologic and pathologic pregnancies

Lintao, R. C. V., Kammala, A. K., Radnaa, E., Bettayeb, M., Vincent, K. L., Patrikeev, I., Yaklic, J., Bonney, E. A. & Menon, R., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1256945.

Research output: Contribution to journal › Article › peer-review

Open Access

Cytochrome P450-mediated alterations in clinical pharmacokinetic parameters of conventional drugs coadministered with piperine: a systematic review and meta-analysis

Pradeepa, B. R., Vijayakumar, T. M., Manikandan, K. & Kammala, A. K., Sep 2023, In: Journal of Herbal Medicine. 41, 100713.

Research output: Contribution to journal › Review article › peer-review

2024

Endocrine-disrupting compounds and their impact on human placental function: evidence from placenta organ-on-chip studies

Vidal, M. S., Richardson, L. S., Kumar Kammala, A., Kim, S., Lam, P. Y., Cherukuri, R., Thomas, T. J., Bettayeb, M., Han, A., Rusyn, I. & Menon, R., Feb 5 2024, In: Lab on a Chip. 24, 6, p. 1727-1749 23 p.

Research output: Contribution to journal › Article › peer-review

Ananth Kumar Kammala, PhD

Research output

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