Agenor Limon-Ruiz

2023

Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia

Schulmann, A., Marenco, S., Vawter, M. P., Akula, N., Limon, A., Mandal, A., Auluck, P. K., Patel, Y., Lipska, B. K. & McMahon, F. J., Dec 2023, In: Translational psychiatry. 13, 1, 93.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change

Scaduto, P., Lauterborn, J. C., Cox, C. D., Fracassi, A., Zeppillo, T., Gutierrez, B. A., Keene, C. D., Crane, P. K., Mukherjee, S., Russell, W. K., Taglialatela, G. & Limon, A., Mar 2023, In: Acta Neuropathologica. 145, 3, p. 303-324 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Transcriptional and bioinformatic analysis of GABA_A receptors expressed in oligodendrocyte progenitor cells from the human brain

Gutierrez, B. A., González-Coronel, J. M., Arellano, R. O. & Limon, A., 2023, In: Frontiers in Molecular Neuroscience. 16, 1279232.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Functional impairment of cortical AMPA receptors in schizophrenia

Zeppillo, T., Schulmann, A., Macciardi, F., Hjelm, B. E., Föcking, M., Sequeira, P. A., Guella, I., Cotter, D., Bunney, W. E., Limon, A. & Vawter, M. P., Nov 2022, In: Schizophrenia Research. 249, p. 25-37 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Microtransplantation of Postmortem Native Synaptic mGluRs Receptors into Xenopus Oocytes for Their Functional Analysis

Miller, B., Moreno, N., Gutierrez, B. A. & Limon, A., Oct 2022, In: Membranes. 12, 10, 931.

Research output: Contribution to journal › Article › peer-review

Open Access

Microtransplantation of Synaptic Membranes to Reactivate Human Synaptic Receptors for Functional Studies

Miller, B., Powell, A., Gutierrez, B. A. & Limon, A., Jul 2022, In: Journal of Visualized Experiments. 2022, 185, e64024.

Research output: Contribution to journal › Article › peer-review

Synaptic Disruption by Soluble Oligomers in Patients with Alzheimer’s and Parkinson’s Disease

Gutierrez, B. A. & Limon, A., Jul 2022, In: Biomedicines. 10, 7, 1743.

Research output: Contribution to journal › Review article › peer-review

Open Access

2021

Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Lauterborn, J. C., Scaduto, P., Cox, C. D., Schulmann, A., Lynch, G., Gall, C. M., Keene, C. D. & Limon, A., Dec 1 2021, In: Nature communications. 12, 1, 2603.

Research output: Contribution to journal › Article › peer-review

Open Access

Transcriptomic expression of AMPA receptor subunits and their auxiliary proteins in the human brain

Shen, K. & Limon, A., Jun 11 2021, In: Neuroscience Letters. 755, 135938.

Research output: Contribution to journal › Article › peer-review

Open Access

GABA_A receptors expressed in oligodendrocytes cultured from the neonatal rat contain a3 and g1 subunits and present differential functional and pharmacological properties

Ordaz, R. P., Garay, E., Limon, A., Pérez-Samartín, A., Sánchez-Gómez, M. V., Robles-Martínez, L., Cisneros-Mejorado, A., Matute, C. & Arellano, R. O., Feb 1 2021, In: Molecular pharmacology. 99, 2, p. 133-146 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2020

Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals

Scaduto, P., Sequeira, A., Vawter, M. P., Bunney, W. & Limon, A., Dec 1 2020, In: Scientific reports. 10, 1, 8626.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Regional transcriptome analysis of AMPA and GABA_A receptor subunit expression generates E/I signatures of the human brain

Shen, K., Zeppillo, T. & Limon, A., Dec 1 2020, In: Scientific reports. 10, 1, 11352.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Expression and Function of GABA Receptors in Myelinating Cells

Serrano-Regal, M. P., Bayón-Cordero, L., Ordaz, R. P., Garay, E., Limon, A., Arellano, R. O., Matute, C. & Sánchez-Gómez, M. V., Aug 21 2020, In: Frontiers in Cellular Neuroscience. 14, 256.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

Tonic Calcium-Activated Chloride Current Sustained by ATP Release and Highly Desensitizing Human P2X1 Receptors

Limon, A., Hagopian, G., Reyes-Ruiz, J. M. & Miledi, R., Jul 15 2020, In: Neuroscience. 439, p. 332-341 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers

Singh, A., Allen, D., Fracassi, A., Tumurbaatar, B., Natarajan, C., Scaduto, P., Woltjer, R., Kayed, R., Limon, A., Krishnan, B., Taglialatela, G. & Abisambra, J., 2020, In: Journal of Alzheimer's Disease. 78, 4, p. 1661-1678 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2019

Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA_A receptors

Limon, A., Delbruck, E., Yassine, A., Pandya, D., Myers, R. M., Barchas, J. D., Lee, F., Schatzberg, Watson, S. J., Akil, H., Bunney, W. E., Vawter, M. P. & Sequeira, A., Dec 1 2019, In: Translational psychiatry. 9, 1, 218.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Human brain transcriptome analysis finds region- and subject-specific expression signatures of GABA_AR subunits

Sequeira, A., Shen, K., Gottlieb, A. & Limon, A., Dec 1 2019, In: Communications Biology. 2, 1, 153.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Nicotine Acts on Cholinergic Signaling Mechanisms to Directly Modulate Choroid Plexus Function

Lallai, V., Grimes, N., Fowler, J. P., Sequeira, P. A., Cartagena, P., Limon-Ruiz, A., Coutts, M., Monuki, E. S., Bunney, W., Demuro, A. & Fowler, C. D., Mar 1 2019, In: eNeuro. 6, 2

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2018

Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease

Baglietto-Vargas, D., Prieto, G. A., Limon, A., Forner, S., Rodriguez-Ortiz, C. J., Ikemura, K., Ager, R. R., Medeiros, R., Trujillo-Estrada, L., Martini, A. C., Kitazawa, M., Davila, J. C., Cotman, C. W., Gutierrez, A. & LaFerla, F. M., Aug 2018, In: Aging cell. 17, 4, e12791.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

2016

Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission

Limon, A., Mamdani, F., Hjelm, B. E., Vawter, M. P. & Sequeira, A., Jul 1 2016, In: Neuroscience and Biobehavioral Reviews. 66, p. 80-91 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

Dipicrylamine Modulates GABAr1 Receptors through Interactions with Residues in the TM4 and Cys-Loop Domains

Limon, A., Estrada-Mondragón, A., Reyes Ruiz, J. M. & Miledi, R., Apr 2016, In: Molecular pharmacology. 89, 4, p. 446-456 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2015

Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABA_A and GABAρ receptors

Candelario, M., Cuellar, E., Reyes-Ruiz, J. M., Darabedian, N., Feimeng, Z., Miledi, R., Russo-Neustadt, A. & Limon, A., Jun 22 2015, In: Journal of Ethnopharmacology. 171, p. 264-272 9 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

2014

Analysis of free ACh and 5-HT in milk from four different species and their bioactivity on 5-HT₃ and nACh receptors

Gallegos-Perez, J. L., Limon, A., Reyes-Ruiz, J. M., Alshanqeeti, A. S., Aljohi, M. A. & Miledi, R., Jul 2014, In: Food and Function. 5, 7, p. 1489-1494 6 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Cloning and characterization of the ionotropic GABA receptor subunit ρ1 from pig (Sus scrofa)

Reyes-Ruiz, J. M., Limon, A. & Miledi, R., Jan 13 2014, In: Neuroscience Letters. 558, p. 78-81 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

The endogenous GABA bioactivity of camel, bovine, goat and human milks

Limon, A., Gallegos-Perez, J. L., Reyes-Ruiz, J. M., Aljohi, M. A., Alshanqeeti, A. S. & Miledi, R., 2014, In: Food Chemistry. 145, p. 481-487 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2013

Identity, expression and functional role of the sodium-activated potassium current in vestibular ganglion afferent neurons

Cervantes, B., Vega, R., Limón, A. & Soto, E., Jun 4 2013, In: Neuroscience. 240, p. 163-175 13 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Profiling neurotransmitter receptor expression in the Ambystoma mexicanum brain

Reyes-Ruiz, J. M., Limon, A., Korn, M. J., Nakamura, P. A., Shirkey, N. J., Wong, J. K. & Miledi, R., Mar 22 2013, In: Neuroscience Letters. 538, p. 32-37 6 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Microtransplantation of cellular membranes from squid stellate ganglion reveals ionotropic GABA receptors

Conti, L., Limon, A., Palma, E. & Miledi, R., Feb 1 2013, In: Biological Bulletin. 224, 1, p. 47-52 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2012

Loss of functional GABA _A receptors in the Alzheimer diseased brain

Limon, A., Reyes-Ruiz, J. M. & Miledi, R., Jun 19 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 25, p. 10071-10076 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

145 Scopus citations

Dopamine and serotonin modulate human GABAρ1 receptors expressed in Xenopus laevis oocytes

Ochoa-De La Paz, L. D., Estrada-Mondragón, A., Limón, A., Miledi, R. & Martínez-Torres, A., Feb 15 2012, In: ACS chemical neuroscience. 3, 2, p. 96-104 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2010

Kaitocephalin antagonism of glutamate receptors expressed in xenopus oocytes

Limon, A., Reyes-Ruiz, J. M., Vaswani, R. G., Chamberlin, A. R. & Miledi, R., Mar 17 2010, In: ACS chemical neuroscience. 1, 3, p. 175-181 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

2009

The muscarinic inhibition of the potassium M-current modulates the action-potential discharge in the vestibular primary-afferent neurons of the rat

Pérez, C., Limón, A., Vega, R. & Soto, E., Feb 18 2009, In: Neuroscience. 158, 4, p. 1662-1674 13 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-kaitocephalin

Vaswani, R. G., Limon, A., Reyes-Ruiz, J. M., Miledi, R. & Chamberlin, A. R., Jan 1 2009, In: Bioorganic and Medicinal Chemistry Letters. 19, 1, p. 132-135 4 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2008

Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes

Limon, A., Reyes-Ruiz, J. M. & Miledi, R., Aug 5 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 31, p. 10973-10977 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2007

Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus

Limon, A., Reyes-Ruiz, J. M., Eusebi, F. & Miledi, R., Sep 25 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 39, p. 15526-15530 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Síndrome del espectro autista. Importancia del diagnóstico temprano

Translated title of the contribution: Autism spectrum disorder. Importance of early diagnosisLimon, A., 2007, In: Gaceta Medica de Mexico. 143, 1, p. 73-78 6 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

2006

Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine

Cohen, J. L., Limon, A., Miledi, R. & Chamberlin, A. R., Apr 15 2006, In: Bioorganic and Medicinal Chemistry Letters. 16, 8, p. 2189-2194 6 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

2005

Ca²⁺-activated K⁺-current density is correlated with soma size in rat vestibular-afferent neurons in culture

Limón, A., Pérez, C., Vega, R. & Soto, E., Dec 2005, In: Journal of neurophysiology. 94, 6, p. 3751-3761 11 p.

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

2003

pH modulates the vestibular afferent discharge and its response to excitatory amino acids

Vega, R., Mercado, F., Chávez, H., Limón, A., Almanza, A., Ortega, A., Pérez, M. E. & Soto, E., Jul 18 2003, In: NeuroReport. 14, 10, p. 1327-1328 2 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2023

A method to study human synaptic protein-protein interactions by using flow cytometry coupled to proximity ligation assay (Syn-FlowPLA)

Marcatti, M., Jamison, D., Fracassi, A., Zhang, W. R., Limon, A. & Taglialatela, G., Aug 1 2023, In: Journal of Neuroscience Methods. 396, 109920.

Research output: Contribution to journal › Article › peer-review

2002

Características morfológicas y electrofisiológicas de las neuronas del ganglio vestibular en cultivo

Translated title of the contribution: Morphologic and electrophysiologic characteristics of vestibular ganglion neurons in cultureSoto, E., Limón, A., Ortega, A. & Vega, R., 2002, In: Gaceta Medica de Mexico. 138, 1, p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

2024

Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets

Omidsalar, A. A., McCullough, C. G., Xu, L., Boedijono, S., Gerke, D., Webb, M. G., Manojlovic, Z., Sequeira, A., Lew, M. F., Santorelli, M., Serrano, G. E., Beach, T. G., Limon, A., Vawter, M. P. & Hjelm, B. E., Dec 2024, In: Communications Biology. 7, 1, 200.

Research output: Contribution to journal › Article › peer-review

Open Access

2011

GABAergic drugs and Alzheimer's disease

Limon, A., Reyes-Ruiz, J. M. & Miledi, R., Feb 2011, In: Future Medicinal Chemistry. 3, 2, p. 149-153 5 p.

Research output: Contribution to journal › Comment/debate › peer-review

17 Scopus citations

2023

The Xenopus Oocyte: A Tool for Membrane Biology

Limon, A. & Mattei, C., Oct 2023, In: Membranes. 13, 10, 831.

Research output: Contribution to journal › Editorial › peer-review

Open Access

Agenor Limon-Ruiz, PHD, MSc

Research output

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